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Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients--Report of a Phase I/IIa Clinical Trial.
Legat A, Maby-El Hajjami H, Baumgaertner P, Cagnon L, Abed Maillard S, Geldhof C, Iancu EM, Lebon L, Guillaume P, Dojcinovic D, Michielin O, Romano E, Berthod G, Rimoldi D, Triebel F, Luescher I, Rufer N, Speiser DE. Legat A, et al. Clin Cancer Res. 2016 Mar 15;22(6):1330-40. doi: 10.1158/1078-0432.CCR-15-1212. Epub 2015 Oct 23. Clin Cancer Res. 2016. PMID: 26500235 Free article. Clinical Trial.
Vaccination of stage III/IV melanoma patients with long NY-ESO-1 peptide and CpG-B elicits robust CD8+ and CD4+ T-cell responses with multiple specificities including a novel DR7-restricted epitope.
Baumgaertner P, Costa Nunes C, Cachot A, Maby-El Hajjami H, Cagnon L, Braun M, Derré L, Rivals JP, Rimoldi D, Gnjatic S, Abed Maillard S, Marcos Mondéjar P, Protti MP, Romano E, Michielin O, Romero P, Speiser DE, Jandus C. Baumgaertner P, et al. Oncoimmunology. 2016 Sep 9;5(10):e1216290. doi: 10.1080/2162402X.2016.1216290. eCollection 2016. Oncoimmunology. 2016. PMID: 27853637 Free PMC article.
Low Avidity T Cells Do Not Hinder High Avidity T Cell Responses Against Melanoma.
Ioannidou K, Randin O, Semilietof A, Maby-El Hajjami H, Baumgaertner P, Vanhecke D, Speiser DE. Ioannidou K, et al. Among authors: maby el hajjami h. Front Immunol. 2019 Sep 6;10:2115. doi: 10.3389/fimmu.2019.02115. eCollection 2019. Front Immunol. 2019. PMID: 31555299 Free PMC article. Clinical Trial.
Inflammatory B cells correlate with failure to checkpoint blockade in melanoma patients.
de Jonge K, Tillé L, Lourenco J, Maby-El Hajjami H, Nassiri S, Racle J, Gfeller D, Delorenzi M, Verdeil G, Baumgaertner P, Speiser DE. de Jonge K, et al. Among authors: maby el hajjami h. Oncoimmunology. 2021 Feb 2;10(1):1873585. doi: 10.1080/2162402X.2021.1873585. Oncoimmunology. 2021. PMID: 33643691 Free PMC article.
Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma.
Bordry N, Broggi MAS, de Jonge K, Schaeuble K, Gannon PO, Foukas PG, Danenberg E, Romano E, Baumgaertner P, Fankhauser M, Wald N, Cagnon L, Abed-Maillard S, Maby-El Hajjami H, Murray T, Ioannidou K, Letovanec I, Yan P, Michielin O, Matter M, Swartz MA, Speiser DE. Bordry N, et al. Among authors: maby el hajjami h. Oncoimmunology. 2018 May 31;7(8):e1462878. doi: 10.1080/2162402X.2018.1462878. eCollection 2018. Oncoimmunology. 2018. PMID: 30221058 Free PMC article.
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