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Loss of lung microvascular endothelial Piezo2 expression impairs NO synthesis, induces EndMT, and is associated with pulmonary hypertension.
Tian S, Cai Z, Sen P, van Uden D, van de Kamp E, Thuillet R, Tu L, Guignabert C, Boomars K, Van der Heiden K, Brandt MM, Merkus D. Tian S, et al. Among authors: brandt mm. Am J Physiol Heart Circ Physiol. 2022 Nov 1;323(5):H958-H974. doi: 10.1152/ajpheart.00220.2022. Epub 2022 Sep 23. Am J Physiol Heart Circ Physiol. 2022. PMID: 36149769 Free article.
CXCL4 drives fibrosis by promoting several key cellular and molecular processes.
Affandi AJ, Carvalheiro T, Ottria A, de Haan JJ, Brans MAD, Brandt MM, Tieland RG, Lopes AP, Fernández BM, Bekker CPJ, van der Linden M, Zimmermann M, Giovannone B, Wichers CGK, Garcia S, de Kok M, Stifano G, Xu YJ, Kowalska MA, Waasdorp M, Cheng C, Gibbs S, de Jager SCA, van Roon JAG, Radstake TRDJ, Marut W. Affandi AJ, et al. Among authors: brandt mm. Cell Rep. 2022 Jan 4;38(1):110189. doi: 10.1016/j.celrep.2021.110189. Cell Rep. 2022. PMID: 34986347 Free article.
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Extracellular Matrix Remodeling during Left Ventricular Diastolic Dysfunction and Heart Failure with Preserved Ejection Fraction: A Systematic Review and Meta-Analysis.
Krebber MM, van Dijk CGM, Vernooij RWM, Brandt MM, Emter CA, Rau CD, Fledderus JO, Duncker DJ, Verhaar MC, Cheng C, Joles JA. Krebber MM, et al. Among authors: brandt mm. Int J Mol Sci. 2020 Sep 14;21(18):6742. doi: 10.3390/ijms21186742. Int J Mol Sci. 2020. PMID: 32937927 Free PMC article.
Both male and female obese ZSF1 rats develop cardiac dysfunction in obesity-induced heart failure with preserved ejection fraction.
Nguyen ITN, Brandt MM, van de Wouw J, van Drie RWA, Wesseling M, Cramer MJ, de Jager SCA, Merkus D, Duncker DJ, Cheng C, Joles JA, Verhaar MC. Nguyen ITN, et al. Among authors: brandt mm. PLoS One. 2020 May 6;15(5):e0232399. doi: 10.1371/journal.pone.0232399. eCollection 2020. PLoS One. 2020. PMID: 32374790 Free PMC article.
A new microfluidic model that allows monitoring of complex vascular structures and cell interactions in a 3D biological matrix.
van Dijk CGM, Brandt MM, Poulis N, Anten J, van der Moolen M, Kramer L, Homburg EFGA, Louzao-Martinez L, Pei J, Krebber MM, van Balkom BWM, de Graaf P, Duncker DJ, Verhaar MC, Luttge R, Cheng C. van Dijk CGM, et al. Among authors: brandt mm. Lab Chip. 2020 May 19;20(10):1827-1844. doi: 10.1039/d0lc00059k. Lab Chip. 2020. PMID: 32330215
Control of Angiogenesis via a VHL/miR-212/132 Axis.
Lei Z, Klasson TD, Brandt MM, van de Hoek G, Logister I, Cheng C, Doevendans PA, Sluijter JPG, Giles RH. Lei Z, et al. Among authors: brandt mm. Cells. 2020 Apr 19;9(4):1017. doi: 10.3390/cells9041017. Cells. 2020. PMID: 32325871 Free PMC article.
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