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Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells.
Zhang Q, Lu Y, Ding Y, Zhai J, Ji Q, Ma W, Yang M, Fan H, Long J, Tong Z, Shi Y, Jia Y, Han B, Zhang W, Qiu C, Ma X, Li Q, Shi Q, Zhang H, Li D, Zhang J, Lin J, Li LY, Gao Y, Chen Y. Zhang Q, et al. Among authors: ma w, ma x. J Med Chem. 2012 Oct 25;55(20):8757-69. doi: 10.1021/jm301064b. Epub 2012 Oct 11. J Med Chem. 2012. PMID: 22985027
Total synthesis of tubulysin U and its C-4 epimer.
Yang XD, Dong CM, Chen J, Ding YH, Liu Q, Ma XY, Zhang Q, Chen Y. Yang XD, et al. Chem Asian J. 2013 Jun;8(6):1213-22. doi: 10.1002/asia.201300051. Epub 2013 Apr 10. Chem Asian J. 2013. PMID: 23576385
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