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Year Number of Results
2020 3
2021 4
2022 6
2023 6
2024 0

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17 results

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Page 1
HLA-E-restricted SARS-CoV-2-specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation.
Yang H, Sun H, Brackenridge S, Zhuang X, Wing PAC, Quastel M, Walters L, Garner L, Wang B, Yao X, Felce SL, Peng Y, Moore S, Peeters BWA, Rei M, Canto Gomes J, Tomas A, Davidson A, Semple MG, Turtle LCW, Openshaw PJM, Baillie JK, Mentzer AJ, Klenerman P; ISARIC4C Investigators; Borrow P, Dong T, McKeating JA, Gillespie GM, McMichael AJ. Yang H, et al. Sci Immunol. 2023 Jun 30;8(84):eabl8881. doi: 10.1126/sciimmunol.abl8881. Epub 2023 Jun 30. Sci Immunol. 2023. PMID: 37390223
Prolonged T-cell activation and long COVID symptoms independently associate with severe COVID-19 at 3 months.
Santopaolo M, Gregorova M, Hamilton F, Arnold D, Long A, Lacey A, Oliver E, Halliday A, Baum H, Hamilton K, Milligan R, Pearce O, Knezevic L, Morales Aza B, Milne A, Milodowski E, Jones E, Lazarus R, Goenka A, Finn A, Maskell N, Davidson AD, Gillespie K, Wooldridge L, Rivino L. Santopaolo M, et al. Elife. 2023 Jun 13;12:e85009. doi: 10.7554/eLife.85009. Elife. 2023. PMID: 37310006 Free PMC article.
An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity.
Wing PAC, Schmidt NM, Peters R, Erdmann M, Brown R, Wang H, Swadling L; COVIDsortium Investigators; Newman J, Thakur N, Shionoya K, Morgan SB, Hinks TS, Watashi K, Bailey D, Hansen SB, Davidson AD, Maini MK, McKeating JA. Wing PAC, et al. PLoS Pathog. 2023 May 3;19(5):e1011323. doi: 10.1371/journal.ppat.1011323. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37134108 Free PMC article.
The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection.
Goldswain H, Dong X, Penrice-Randal R, Alruwaili M, Shawli GT, Prince T, Williamson MK, Raghwani J, Randle N, Jones B, Donovan-Banfield I, Salguero FJ, Tree JA, Hall Y, Hartley C, Erdmann M, Bazire J, Jearanaiwitayakul T, Semple MG, Openshaw PJM, Baillie JK; ISARIC4C Investigators; Emmett SR, Digard P, Matthews DA, Turtle L, Darby AC, Davidson AD, Carroll MW, Hiscox JA. Goldswain H, et al. Genome Biol. 2023 Mar 13;24(1):47. doi: 10.1186/s13059-023-02881-5. Genome Biol. 2023. PMID: 36915185 Free PMC article.
Development and evaluation of low-volume tests to detect and characterize antibodies to SARS-CoV-2.
Halliday A, Long AE, Baum HE, Thomas AC, Shelley KL, Oliver E, Gupta K, Francis O, Williamson MK, Di Bartolo N, Randell MJ, Ben-Khoud Y, Kelland I, Mortimer G, Ball O, Plumptre C, Chandler K, Obst U, Secchi M, Piemonti L, Lampasona V, Smith J, Gregorova M, Knezevic L, Metz J, Barr R, Morales-Aza B, Oliver J, Collingwood L, Hitchings B, Ring S, Wooldridge L, Rivino L, Timpson N, McKernon J, Muir P, Hamilton F, Arnold D, Woolfson DN, Goenka A, Davidson AD, Toye AM, Berger I, Bailey M, Gillespie KM, Williams AJK, Finn A. Halliday A, et al. Front Immunol. 2022 Nov 9;13:968317. doi: 10.3389/fimmu.2022.968317. eCollection 2022. Front Immunol. 2022. PMID: 36439154 Free PMC article.
The free fatty acid-binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron.
Toelzer C, Gupta K, Yadav SKN, Hodgson L, Williamson MK, Buzas D, Borucu U, Powers K, Stenner R, Vasileiou K, Garzoni F, Fitzgerald D, Payré C, Gautam G, Lambeau G, Davidson AD, Verkade P, Frank M, Berger I, Schaffitzel C. Toelzer C, et al. Sci Adv. 2022 Nov 25;8(47):eadc9179. doi: 10.1126/sciadv.adc9179. Epub 2022 Nov 23. Sci Adv. 2022. PMID: 36417532 Free PMC article.
The dynamics of SARS-CoV-2 infectivity with changes in aerosol microenvironment.
Oswin HP, Haddrell AE, Otero-Fernandez M, Mann JFS, Cogan TA, Hilditch TG, Tian J, Hardy DA, Hill DJ, Finn A, Davidson AD, Reid JP. Oswin HP, et al. Proc Natl Acad Sci U S A. 2022 Jul 5;119(27):e2200109119. doi: 10.1073/pnas.2200109119. Epub 2022 Jun 28. Proc Natl Acad Sci U S A. 2022. PMID: 35763573 Free PMC article.
Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2.
Gupta K, Toelzer C, Williamson MK, Shoemark DK, Oliveira ASF, Matthews DA, Almuqrin A, Staufer O, Yadav SKN, Borucu U, Garzoni F, Fitzgerald D, Spatz J, Mulholland AJ, Davidson AD, Schaffitzel C, Berger I. Gupta K, et al. Nat Commun. 2022 Jan 11;13(1):222. doi: 10.1038/s41467-021-27881-6. Nat Commun. 2022. PMID: 35017512 Free PMC article.
17 results