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The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming.
PLoS Pathog. 2019 Jun 21;15(6):e1007871. doi: 10.1371/journal.ppat.1007871. eCollection 2019 Jun.
PLoS Pathog. 2019.
PMID: 31226171
Free PMC article.
Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4.
Pizzuto M, Lonez C, Baroja-Mazo A, Martínez-Banaclocha H, Tourlomousis P, Gangloff M, Pelegrin P, Ruysschaert JM, Gay NJ, Bryant CE.
Pizzuto M, et al.
Cell Mol Life Sci. 2019 Sep;76(18):3667-3678. doi: 10.1007/s00018-019-03113-5. Epub 2019 May 6.
Cell Mol Life Sci. 2019.
PMID: 31062071
Free PMC article.
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