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Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
Baddock HT, Brolih S, Yosaatmadja Y, Ratnaweera M, Bielinski M, Swift LP, Cruz-Migoni A, Fan H, Keown JR, Walker AP, Morris GM, Grimes JM, Fodor E, Schofield CJ, Gileadi O, McHugh PJ. Baddock HT, et al. Nucleic Acids Res. 2022 Feb 22;50(3):1484-1500. doi: 10.1093/nar/gkab1303. Nucleic Acids Res. 2022. PMID: 35037045 Free PMC article.
Repeat expansions confer WRN dependence in microsatellite-unstable cancers.
van Wietmarschen N, Sridharan S, Nathan WJ, Tubbs A, Chan EM, Callen E, Wu W, Belinky F, Tripathi V, Wong N, Foster K, Noorbakhsh J, Garimella K, Cruz-Migoni A, Sommers JA, Huang Y, Borah AA, Smith JT, Kalfon J, Kesten N, Fugger K, Walker RL, Dolzhenko E, Eberle MA, Hayward BE, Usdin K, Freudenreich CH, Brosh RM Jr, West SC, McHugh PJ, Meltzer PS, Bass AJ, Nussenzweig A. van Wietmarschen N, et al. Nature. 2020 Oct;586(7828):292-298. doi: 10.1038/s41586-020-2769-8. Epub 2020 Sep 30. Nature. 2020. PMID: 32999459 Free PMC article.
XPF-ERCC1: Linchpin of DNA crosslink repair.
McHugh PJ. McHugh PJ. PLoS Genet. 2020 Apr 9;16(4):e1008616. doi: 10.1371/journal.pgen.1008616. eCollection 2020 Apr. PLoS Genet. 2020. PMID: 32271747 Free PMC article. No abstract available.