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2017 6
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Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function.
Román-Fernández A, Mansour MA, Kugeratski FG, Anand J, Sandilands E, Galbraith L, Rakovic K, Freckmann EC, Cumming EM, Park J, Nikolatou K, Lilla S, Shaw R, Strachan D, Mason S, Patel R, McGarry L, Katoch A, Campbell KJ, Nixon C, Miller CJ, Leung HY, Le Quesne J, Norman JC, Zanivan S, Blyth K, Bryant DM. Román-Fernández A, et al. Sci Adv. 2023 Feb 3;9(5):eabq1858. doi: 10.1126/sciadv.abq1858. Epub 2023 Feb 3. Sci Adv. 2023. PMID: 36735782 Free PMC article.
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics.
Koessinger AL, Cloix C, Koessinger D, Heiland DH, Bock FJ, Strathdee K, Kinch K, Martínez-Escardó L, Paul NR, Nixon C, Malviya G, Jackson MR, Campbell KJ, Stevenson K, Davis S, Elmasry Y, Ahmed A, O'Prey J, Ichim G, Schnell O, Stewart W, Blyth K, Ryan KM, Chalmers AJ, Norman JC, Tait SWG. Koessinger AL, et al. Cell Death Differ. 2022 Oct;29(10):2089-2104. doi: 10.1038/s41418-022-01001-3. Epub 2022 Apr 26. Cell Death Differ. 2022. PMID: 35473984 Free PMC article.
Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Jamshidiha M, Lanyon-Hogg T, Sutherell CL, Craven GB, Tersa M, De Vita E, Brustur D, Pérez-Dorado I, Hassan S, Petracca R, Morgan RM, Sanz-Hernández M, Norman JC, Armstrong A, Mann DJ, Cota E, Tate EW. Jamshidiha M, et al. RSC Med Chem. 2021 Dec 16;13(2):150-155. doi: 10.1039/d1md00225b. eCollection 2022 Feb 23. RSC Med Chem. 2021. PMID: 35308027 Free PMC article.
21 results