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PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer.
Cancer Res. 2021 Jun 1;81(11):2888-2902. doi: 10.1158/0008-5472.CAN-21-0628.
Cancer Res. 2021.
PMID: 33888468
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.
Rother MB, Pellegrino S, Smith R, Gatti M, Meisenberg C, Wiegant WW, Luijsterburg MS, Imhof R, Downs JA, Vertegaal ACO, Huet S, Altmeyer M, van Attikum H.
Rother MB, et al.
Nat Commun. 2020 Nov 13;11(1):5775. doi: 10.1038/s41467-020-19502-5.
Nat Commun. 2020.
PMID: 33188175
Free PMC article.
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Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability.
Meisenberg C, Pinder SI, Hopkins SR, Wooller SK, Benstead-Hume G, Pearl FMG, Jeggo PA, Downs JA.
Meisenberg C, et al.
Mol Cell. 2019 Jan 17;73(2):212-223.e7. doi: 10.1016/j.molcel.2018.11.001. Epub 2018 Dec 13.
Mol Cell. 2019.
PMID: 30554942
Free PMC article.
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Chromatin modifiers and remodellers in DNA repair and signalling.
Jeggo PA, Downs JA, Gasser SM.
Jeggo PA, et al.
Philos Trans R Soc Lond B Biol Sci. 2017 Oct 5;372(1731):20160279. doi: 10.1098/rstb.2016.0279.
Philos Trans R Soc Lond B Biol Sci. 2017.
PMID: 28847816
Free PMC article.
No abstract available.
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