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HAM-ART: An optimised culture-free Hi-C metagenomics pipeline for tracking antimicrobial resistance genes in complex microbial communities.
Kalmar L, Gupta S, Kean IRL, Ba X, Hadjirin N, Lay EM, de Vries SPW, Bateman M, Bartlet H, Hernandez-Garcia J, Tucker AW, Restif O, Stevens MP, Wood JLN, Maskell DJ, Grant AJ, Holmes MA. Kalmar L, et al. PLoS Genet. 2022 Mar 14;18(3):e1009776. doi: 10.1371/journal.pgen.1009776. eCollection 2022 Mar. PLoS Genet. 2022. PMID: 35286304 Free PMC article.
Emergence of methicillin resistance predates the clinical use of antibiotics.
Larsen J, Raisen CL, Ba X, Sadgrove NJ, Padilla-González GF, Simmonds MSJ, Loncaric I, Kerschner H, Apfalter P, Hartl R, Deplano A, Vandendriessche S, Černá Bolfíková B, Hulva P, Arendrup MC, Hare RK, Barnadas C, Stegger M, Sieber RN, Skov RL, Petersen A, Angen Ø, Rasmussen SL, Espinosa-Gongora C, Aarestrup FM, Lindholm LJ, Nykäsenoja SM, Laurent F, Becker K, Walther B, Kehrenberg C, Cuny C, Layer F, Werner G, Witte W, Stamm I, Moroni P, Jørgensen HJ, de Lencastre H, Cercenado E, García-Garrote F, Börjesson S, Hæggman S, Perreten V, Teale CJ, Waller AS, Pichon B, Curran MD, Ellington MJ, Welch JJ, Peacock SJ, Seilly DJ, Morgan FJE, Parkhill J, Hadjirin NF, Lindsay JA, Holden MTG, Edwards GF, Foster G, Paterson GK, Didelot X, Holmes MA, Harrison EM, Larsen AR. Larsen J, et al. Nature. 2022 Feb;602(7895):135-141. doi: 10.1038/s41586-021-04265-w. Epub 2022 Jan 5. Nature. 2022. PMID: 34987223 Free PMC article.
Closely related Lak megaphages replicate in the microbiomes of diverse animals.
Crisci MA, Chen LX, Devoto AE, Borges AL, Bordin N, Sachdeva R, Tett A, Sharrar AM, Segata N, Debenedetti F, Bailey M, Burt R, Wood RM, Rowden LJ, Corsini PM, van Winden S, Holmes MA, Lei S, Banfield JF, Santini JM. Crisci MA, et al. iScience. 2021 Jul 16;24(8):102875. doi: 10.1016/j.isci.2021.102875. eCollection 2021 Aug 20. iScience. 2021. PMID: 34386733 Free PMC article.
30 results