MR/K000551/1/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2014	2
2015	4
2016	2
2017	3
2018	1
2024	0

1

Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally.

Phelan J, de Sessions PF, Tientcheu L, Perdigao J, Machado D, Hasan R, Hasan Z, Bergval IL, Anthony R, McNerney R, Antonio M, Portugal I, Viveiros M, Campino S, Hibberd ML, Clark TG. Phelan J, et al. Sci Rep. 2018 Jan 9;8(1):160. doi: 10.1038/s41598-017-18188-y. Sci Rep. 2018. PMID: 29317751 Free PMC article.

2

Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia.

Sengstake S, Bergval IL, Schuitema AR, de Beer JL, Phelan J, de Zwaan R, Clark TG, van Soolingen D, Anthony RM. Sengstake S, et al. BMC Infect Dis. 2017 Jul 12;17(1):491. doi: 10.1186/s12879-017-2594-3. BMC Infect Dis. 2017. PMID: 28697808 Free PMC article.

3

Genetic diversity of next generation antimalarial targets: A baseline for drug resistance surveillance programmes.

Gomes AR, Ravenhall M, Benavente ED, Talman A, Sutherland C, Roper C, Clark TG, Campino S. Gomes AR, et al. Int J Parasitol Drugs Drug Resist. 2017 Aug;7(2):174-180. doi: 10.1016/j.ijpddr.2017.03.001. Epub 2017 Mar 9. Int J Parasitol Drugs Drug Resist. 2017. PMID: 28376349 Free PMC article.

4

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis.

Andreu N, Phelan J, de Sessions PF, Cliff JM, Clark TG, Hibberd ML. Andreu N, et al. Sci Rep. 2017 Feb 8;7:42225. doi: 10.1038/srep42225. Sci Rep. 2017. PMID: 28176867 Free PMC article.

5

The draft genome of Mycobacterium aurum, a potential model organism for investigating drugs against Mycobacterium tuberculosis and Mycobacterium leprae.

Phelan J, Maitra A, McNerney R, Nair M, Gupta A, Coll F, Pain A, Bhakta S, Clark TG. Phelan J, et al. Int J Mycobacteriol. 2015 Sep;4(3):207-16. doi: 10.1016/j.ijmyco.2015.05.001. Epub 2015 Jun 4. Int J Mycobacteriol. 2015. PMID: 27649868 Free article.

6

Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance.

Phelan J, Coll F, McNerney R, Ascher DB, Pires DE, Furnham N, Coeck N, Hill-Cawthorne GA, Nair MB, Mallard K, Ramsay A, Campino S, Hibberd ML, Pain A, Rigouts L, Clark TG. Phelan J, et al. BMC Med. 2016 Mar 23;14:31. doi: 10.1186/s12916-016-0575-9. BMC Med. 2016. PMID: 27005572 Free PMC article.

7

Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages.

Phelan JE, Coll F, Bergval I, Anthony RM, Warren R, Sampson SL, Gey van Pittius NC, Glynn JR, Crampin AC, Alves A, Bessa TB, Campino S, Dheda K, Grandjean L, Hasan R, Hasan Z, Miranda A, Moore D, Panaiotov S, Perdigao J, Portugal I, Sheen P, de Oliveira Sousa E, Streicher EM, van Helden PD, Viveiros M, Hibberd ML, Pain A, McNerney R, Clark TG. Phelan JE, et al. BMC Genomics. 2016 Feb 29;17:151. doi: 10.1186/s12864-016-2467-y. BMC Genomics. 2016. PMID: 26923687 Free PMC article.

8

Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations.

Abdallah AM, Hill-Cawthorne GA, Otto TD, Coll F, Guerra-Assunção JA, Gao G, Naeem R, Ansari H, Malas TB, Adroub SA, Verboom T, Ummels R, Zhang H, Panigrahi AK, McNerney R, Brosch R, Clark TG, Behr MA, Bitter W, Pain A. Abdallah AM, et al. Sci Rep. 2015 Oct 21;5:15443. doi: 10.1038/srep15443. Sci Rep. 2015. PMID: 26487098 Free PMC article.

9

African glucose-6-phosphate dehydrogenase alleles associated with protection from severe malaria in heterozygous females in Tanzania.

Manjurano A, Sepulveda N, Nadjm B, Mtove G, Wangai H, Maxwell C, Olomi R, Reyburn H, Riley EM, Drakeley CJ, Clark TG; MalariaGEN Consortium. Manjurano A, et al. PLoS Genet. 2015 Feb 11;11(2):e1004960. doi: 10.1371/journal.pgen.1004960. eCollection 2015 Feb. PLoS Genet. 2015. PMID: 25671784 Free PMC article.

10

A proportion of mutations fixed in the genomes of in vitro selected isogenic drug-resistant Mycobacterium tuberculosis mutants can be detected as minority variants in the parent culture.

Bergval I, Coll F, Schuitema A, de Ronde H, Mallard K, Pain A, McNerney R, Clark TG, Anthony RM. Bergval I, et al. FEMS Microbiol Lett. 2015 Jan;362(2):1-7. doi: 10.1093/femsle/fnu037. Epub 2014 Dec 4. FEMS Microbiol Lett. 2015. PMID: 25670707

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