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The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma.
Chang C, Rajasekaran M, Qiao Y, Dong H, Wang Y, Xia H, Deivasigamani A, Wu M, Sekar K, Gao H, Sun M, Niu Y, Li Q, Tao L, Yan Z, Wang M, Chen S, Zhao S, Chen D, Li L, Yang F, Gao H, Chen B, Su L, Xu L, Chen Y, Seshachalam VP, Chen G, Gunaratne J, Hong W, Shi J, Chen G, Grierson DS, Chabot B, Xie T, Hui KM, Chen J. Chang C, et al. Nat Commun. 2022 Mar 16;13(1):1363. doi: 10.1038/s41467-022-29016-x. Nat Commun. 2022. PMID: 35296659 Free PMC article.
TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.
Deshaies JE, Shkreta L, Moszczynski AJ, Sidibé H, Semmler S, Fouillen A, Bennett ER, Bekenstein U, Destroismaisons L, Toutant J, Delmotte Q, Volkening K, Stabile S, Aulas A, Khalfallah Y, Soreq H, Nanci A, Strong MJ, Chabot B, Vande Velde C. Deshaies JE, et al. Brain. 2018 May 1;141(5):1320-1333. doi: 10.1093/brain/awy062. Brain. 2018. PMID: 29562314 Free PMC article.