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GATA2 mitotic bookmarking is required for definitive haematopoiesis.
Silvério-Alves R, Kurochkin I, Rydström A, Vazquez Echegaray C, Haider J, Nicholls M, Rode C, Thelaus L, Lindgren AY, Ferreira AG, Brandão R, Larsson J, de Bruijn MFTR, Martin-Gonzalez J, Pereira CF. Silvério-Alves R, et al. Nat Commun. 2023 Aug 14;14(1):4645. doi: 10.1038/s41467-023-40391-x. Nat Commun. 2023. PMID: 37580379 Free PMC article.
The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.
Azzoni E, Frontera V, Anselmi G, Rode C, James C, Deltcheva EM, Demian AS, Brown J, Barone C, Patelli A, Harman JR, Nicholls M, Conway SJ, Morrissey E, Jacobsen SEW, Sparrow DB, Harris AL, Enver T, de Bruijn MFTR. Azzoni E, et al. Cell Rep. 2021 Dec 14;37(11):110103. doi: 10.1016/j.celrep.2021.110103. Cell Rep. 2021. PMID: 34910918 Free PMC article.
The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis.
Muskens IS, Li S, Jackson T, Elliot N, Hansen HM, Myint SS, Pandey P, Schraw JM, Roy R, Anguiano J, Goudevenou K, Siegmund KD, Lupo PJ, de Bruijn MFTR, Walsh KM, Vyas P, Ma X, Roy A, Roberts I, Wiemels JL, de Smith AJ. Muskens IS, et al. Nat Commun. 2021 Feb 5;12(1):821. doi: 10.1038/s41467-021-21064-z. Nat Commun. 2021. PMID: 33547282 Free PMC article.
16 results