MC_G1002464/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2011	1
2012	1
2013	2
2014	1
2015	1
2016	3
2017	1
2019	2
2021	3
2024	0

1

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S; 23andMe Research Team; Voda AI; Bellygenes Initiative; Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M. Eijsbouts C, et al. Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 5. Nat Genet. 2021. PMID: 34741163 Free PMC article.

2

Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine.

Jalanka J, Lam C, Bennett A, Hartikainen A, Crispie F, Finnegan LA, Cotter PD, Spiller R. Jalanka J, et al. J Neurogastroenterol Motil. 2021 Apr 30;27(2):279-291. doi: 10.5056/jnm20205. J Neurogastroenterol Motil. 2021. PMID: 33795545 Free PMC article.

3

Pain Severity Correlates With Biopsy-Mediated Colonic Afferent Activation But Not Psychological Scores in Patients With IBS-D.

Cibert-Goton V, Lam C, Lingaya M, Falcone Y, Wood JN, Bulmer DC, Spiller R. Cibert-Goton V, et al. Clin Transl Gastroenterol. 2021 Feb 22;12(2):e00313. doi: 10.14309/ctg.0000000000000313. Clin Transl Gastroenterol. 2021. PMID: 33617189 Free PMC article.

4

Increased fasting small-bowel water content in untreated coeliac disease and scleroderma as assessed by magnetic resonance imaging.

Lam C, Sanders DS, Lanyon P, Garsed K, Foley S, Pritchard S, Marciani L, Hoad CL, Costigan C, Gowland P, Spiller R. Lam C, et al. United European Gastroenterol J. 2019 Dec;7(10):1353-1360. doi: 10.1177/2050640619860372. Epub 2019 Jun 21. United European Gastroenterol J. 2019. PMID: 31839961 Free PMC article.

5

Abnormalities of mucosal serotonin metabolism and 5-HT₃ receptor subunit 3C polymorphism in irritable bowel syndrome with diarrhoea predict responsiveness to ondansetron.

Gunn D, Garsed K, Lam C, Singh G, Lingaya M, Wahl V, Niesler B, Henry A, Hall IP, Whorwell P, Spiller R. Gunn D, et al. Aliment Pharmacol Ther. 2019 Sep;50(5):538-546. doi: 10.1111/apt.15420. Epub 2019 Jul 24. Aliment Pharmacol Ther. 2019. PMID: 31342534 Free PMC article. Clinical Trial.

6

Distinct Abnormalities of Small Bowel and Regional Colonic Volumes in Subtypes of Irritable Bowel Syndrome Revealed by MRI.

Lam C, Chaddock G, Marciani Laurea L, Costigan C, Cox E, Hoad C, Pritchard S, Gowland P, Spiller R. Lam C, et al. Am J Gastroenterol. 2017 Feb;112(2):346-355. doi: 10.1038/ajg.2016.538. Epub 2016 Dec 13. Am J Gastroenterol. 2017. PMID: 27958282 Free PMC article.

7

Corticotropin-releasing factor increases ascending colon volume after a fructose test meal in healthy humans: a randomized controlled trial.

Murray KA, Lam C, Rehman S, Marciani L, Costigan C, Hoad CL, Lingaya MR, Banwait R, Bawden SJ, Gowland PA, Spiller RC. Murray KA, et al. Am J Clin Nutr. 2016 May;103(5):1318-26. doi: 10.3945/ajcn.115.125047. Epub 2016 Apr 20. Am J Clin Nutr. 2016. PMID: 27099247 Free article. Clinical Trial.

8

A mechanistic multicentre, parallel group, randomised placebo-controlled trial of mesalazine for the treatment of IBS with diarrhoea (IBS-D).

Lam C, Tan W, Leighton M, Hastings M, Lingaya M, Falcone Y, Zhou X, Xu L, Whorwell P, Walls AF, Zaitoun A, Montgomery A, Spiller R. Lam C, et al. Gut. 2016 Jan;65(1):91-9. doi: 10.1136/gutjnl-2015-309122. Epub 2015 Mar 12. Gut. 2016. PMID: 25765462 Free PMC article. Clinical Trial.

9

Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit.

Tooth D, Garsed K, Singh G, Marciani L, Lam C, Fordham I, Fields A, Banwait R, Lingaya M, Layfield R, Hastings M, Whorwell P, Spiller R. Tooth D, et al. Gut. 2014 May;63(5):753-60. doi: 10.1136/gutjnl-2012-304042. Epub 2013 Aug 2. Gut. 2014. PMID: 23911555 Free PMC article. Clinical Trial.

10

Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D): study protocol for a randomised controlled trial.

Leighton MP, Lam C, Mehta S, Spiller RC. Leighton MP, et al. Trials. 2013 Jan 9;14:10. doi: 10.1186/1745-6215-14-10. Trials. 2013. PMID: 23302220 Free PMC article. Clinical Trial.

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