MC_EX_UU_G0800765/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2012	1
2013	9
2014	4
2022	2
2024	0

1

HOIL-1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation.

Kelsall IR, McCrory EH, Xu Y, Scudamore CL, Nanda SK, Mancebo-Gamella P, Wood NT, Knebel A, Matthews SJ, Cohen P. Kelsall IR, et al. EMBO J. 2022 Apr 19;41(8):e109700. doi: 10.15252/embj.2021109700. Epub 2022 Mar 11. EMBO J. 2022. PMID: 35274759 Free PMC article.

2

Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?

Petrova T, Bennett K, Nanda S, Strickson S, Scudamore CL, Prescott AR, Cohen P. Petrova T, et al. PLoS One. 2022 Feb 14;17(2):e0263151. doi: 10.1371/journal.pone.0263151. eCollection 2022. PLoS One. 2022. PMID: 35157702 Free PMC article.

3

An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation.

Zhang J, Clark K, Lawrence T, Peggie MW, Cohen P. Zhang J, et al. Biochem J. 2014 Aug 1;461(3):531-7. doi: 10.1042/BJ20140444. Biochem J. 2014. PMID: 24911653 Free PMC article.

4

Immune diseases caused by mutations in kinases and components of the ubiquitin system.

Cohen P. Cohen P. Nat Immunol. 2014 Jun;15(6):521-9. doi: 10.1038/ni.2892. Nat Immunol. 2014. PMID: 24840983 Free PMC article. Review.

5

The TLR and IL-1 signalling network at a glance.

Cohen P. Cohen P. J Cell Sci. 2014 Jun 1;127(Pt 11):2383-90. doi: 10.1242/jcs.149831. Epub 2014 May 14. J Cell Sci. 2014. PMID: 24829146 Free PMC article. Review.

6

IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation.

Lin KM, Hu W, Troutman TD, Jennings M, Brewer T, Li X, Nanda S, Cohen P, Thomas JA, Pasare C. Lin KM, et al. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):775-80. doi: 10.1073/pnas.1320294111. Epub 2013 Dec 30. Proc Natl Acad Sci U S A. 2014. PMID: 24379360 Free PMC article.

7

Molecular control of the NEMO family of ubiquitin-binding proteins.

Clark K, Nanda S, Cohen P. Clark K, et al. Nat Rev Mol Cell Biol. 2013 Oct;14(10):673-85. doi: 10.1038/nrm3644. Epub 2013 Aug 29. Nat Rev Mol Cell Biol. 2013. PMID: 23989959 Review.

8

Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains.

Emmerich CH, Ordureau A, Strickson S, Arthur JS, Pedrioli PG, Komander D, Cohen P. Emmerich CH, et al. Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15247-52. doi: 10.1073/pnas.1314715110. Epub 2013 Aug 28. Proc Natl Acad Sci U S A. 2013. PMID: 23986494 Free PMC article.

9

ABIN1 dysfunction as a genetic basis for lupus nephritis.

Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G'sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, Adrianto I, Gaffney PM, Stevens AM, Freedman BI, Langefeld CD, Tsao BP, Pons-Estel BA, Jacob CO, Kamen DL, Gilkeson GS, Brown EE, Alarcon GS, Edberg JC, Kimberly RP, Martin J, Merrill JT, Harley JB, Kaufman KM, Reveille JD, Anaya JM, Criswell LA, Vila LM, Petri M, Ramsey-Goldman R, Bae SC, Boackle SA, Vyse TJ, Niewold TB, Cohen P, Powell DW. Caster DJ, et al. J Am Soc Nephrol. 2013 Nov;24(11):1743-54. doi: 10.1681/ASN.2013020148. Epub 2013 Aug 22. J Am Soc Nephrol. 2013. PMID: 23970121 Free PMC article.

10

Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.

Pauls E, Nanda SK, Smith H, Toth R, Arthur JSC, Cohen P. Pauls E, et al. J Immunol. 2013 Sep 1;191(5):2717-30. doi: 10.4049/jimmunol.1203268. Epub 2013 Aug 5. J Immunol. 2013. PMID: 23918981 Free PMC article.

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