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Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.
Schindler M, Würfl S, Benaroch P, Greenough TC, Daniels R, Easterbrook P, Brenner M, Münch J, Kirchhoff F. Schindler M, et al. Among authors: munch j. J Virol. 2003 Oct;77(19):10548-56. doi: 10.1128/jvi.77.19.10548-10556.2003. J Virol. 2003. PMID: 12970439 Free PMC article.
Importance of the N-distal AP-2 binding element in Nef for simian immunodeficiency virus replication and pathogenicity in rhesus macaques.
Brenner M, Münch J, Schindler M, Wildum S, Stolte N, Stahl-Hennig C, Fuchs D, Mätz-Rensing K, Franz M, Heeney J, Ten Haaft P, Swigut T, Hrecka K, Skowronski J, Kirchhoff F. Brenner M, et al. Among authors: munch j. J Virol. 2006 May;80(9):4469-81. doi: 10.1128/JVI.80.9.4469-4481.2006. J Virol. 2006. PMID: 16611907 Free PMC article.
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.
Schindler M, Münch J, Kutsch O, Li H, Santiago ML, Bibollet-Ruche F, Müller-Trutwin MC, Novembre FJ, Peeters M, Courgnaud V, Bailes E, Roques P, Sodora DL, Silvestri G, Sharp PM, Hahn BH, Kirchhoff F. Schindler M, et al. Among authors: munch j. Cell. 2006 Jun 16;125(6):1055-67. doi: 10.1016/j.cell.2006.04.033. Cell. 2006. PMID: 16777597 Free article.
Proline 35 of human immunodeficiency virus type 1 (HIV-1) Vpr regulates the integrity of the N-terminal helix and the incorporation of Vpr into virus particles and supports the replication of R5-tropic HIV-1 in human lymphoid tissue ex vivo.
Votteler J, Studtrucker N, Sörgel S, Münch J, Rücker E, Kirchhoff F, Schick B, Henklein P, Fossen T, Bruns K, Sharma A, Wray V, Schubert U. Votteler J, et al. Among authors: munch j. J Virol. 2007 Sep;81(17):9572-6. doi: 10.1128/JVI.02803-06. Epub 2007 Jun 6. J Virol. 2007. PMID: 17553868 Free PMC article.
565 results