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Memory T cells effectively recognize the SARS-CoV-2 hypermutated BA.2.86 variant.
Müller TR, Gao Y, Wu J, Ribeiro O, Chen P, Bergman P, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Söderdahl G, Smith CIE, Loré K, Chen MS, Ljungman P, Ingelman-Sundberg HM, Ljunggren HG, Österborg A, Sette A, Grifoni A, Aleman S, Buggert M. Müller TR, et al. Cell Host Microbe. 2024 Feb 14;32(2):156-161.e3. doi: 10.1016/j.chom.2023.12.010. Epub 2024 Jan 10. Cell Host Microbe. 2024. PMID: 38211584 Free article.
Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant.
Gao Y, Cai C, Grifoni A, Müller TR, Niessl J, Olofsson A, Humbert M, Hansson L, Österborg A, Bergman P, Chen P, Olsson A, Sandberg JK, Weiskopf D, Price DA, Ljunggren HG, Karlsson AC, Sette A, Aleman S, Buggert M. Gao Y, et al. Among authors: muller tr. Nat Med. 2022 Mar;28(3):472-476. doi: 10.1038/s41591-022-01700-x. Epub 2022 Jan 14. Nat Med. 2022. PMID: 35042228 Free PMC article.
Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination.
Gao Y, Cai C, Wullimann D, Niessl J, Rivera-Ballesteros O, Chen P, Lange J, Cuapio A, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Perez-Potti A, Sekine T, Müller TR, Boulouis C, Kammann T, Parrot T, Muvva JR, Sobkowiak M, Healy K, Bogdanovic G, Muschiol S, Söderdahl G, Österborg A, Hellgren F, Grifoni A, Weiskopf D, Sette A, Loré K, Sällberg Chen M, Ljungman P, Sandberg JK, Smith CIE, Bergman P, Ljunggren HG, Aleman S, Buggert M. Gao Y, et al. Among authors: muller tr. Immunity. 2022 Sep 13;55(9):1732-1746.e5. doi: 10.1016/j.immuni.2022.07.005. Epub 2022 Jul 19. Immunity. 2022. PMID: 35961317 Free PMC article.
Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states.
Müller TR, Sekine T, Trubach D, Niessl J, Chen P, Bergman P, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Olofsson A, Amaya Hernandez SP, Gao Y, Cai C, Söderdahl G, Smith CIE, Österborg A, Loré K, Sällberg Chen M, Ljungman P, Ljunggren HG, Karlsson AC, Saini SK, Aleman S, Buggert M. Müller TR, et al. Sci Transl Med. 2023 Jul 12;15(704):eadg9452. doi: 10.1126/scitranslmed.adg9452. Epub 2023 Jul 12. Sci Transl Med. 2023. PMID: 37437015 Free PMC article.
Protective T cell receptor identification for orthotopic reprogramming of immunity in refractory virus infections.
Stief TA, Kaeuferle T, Müller TR, Döring M, Jablonowski LM, Schober K, Feucht J, Dennehy KM, Willier S, Blaeschke F, Handgretinger R, Lang P, Busch DH, Feuchtinger T. Stief TA, et al. Among authors: muller tr. Mol Ther. 2022 Jan 5;30(1):198-208. doi: 10.1016/j.ymthe.2021.05.021. Epub 2021 May 29. Mol Ther. 2022. PMID: 34058386 Free PMC article.
Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy.
Müller TR, Jarosch S, Hammel M, Leube J, Grassmann S, Bernard B, Effenberger M, Andrä I, Chaudhry MZ, Käuferle T, Malo A, Cicin-Sain L, Steinberger P, Feuchtinger T, Protzer U, Schumann K, Neuenhahn M, Schober K, Busch DH. Müller TR, et al. Cell Rep Med. 2021 Aug 17;2(8):100374. doi: 10.1016/j.xcrm.2021.100374. eCollection 2021 Aug 17. Cell Rep Med. 2021. PMID: 34467251 Free PMC article.
Miniaturized CAR knocked onto CD3ε extends TCR function with CAR specificity under control of endogenous TCR signaling cascade.
Manske K, Dreßler L, Fräßle SP, Effenberger M, Tschulik C, Cletiu V, Benke E, Wagner M, Schober K, Müller TR, Stemberger C, Germeroth L, Busch DH, Poltorak MP. Manske K, et al. Among authors: muller tr. J Immunol Methods. 2024 Mar;526:113617. doi: 10.1016/j.jim.2024.113617. Epub 2024 Jan 11. J Immunol Methods. 2024. PMID: 38215900 Free article.
36 results