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O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
Gonzalez-Rellan MJ, Fondevila MF, Fernandez U, Rodríguez A, Varela-Rey M, Veyrat-Durebex C, Seoane S, Bernardo G, Lopitz-Otsoa F, Fernández-Ramos D, Bilbao J, Iglesias C, Novoa E, Ameneiro C, Senra A, Beiroa D, Cuñarro J, Dp Chantada-Vazquez M, Garcia-Vence M, Bravo SB, Da Silva Lima N, Porteiro B, Carneiro C, Vidal A, Tovar S, Müller TD, Ferno J, Guallar D, Fidalgo M, Sabio G, Herzig S, Yang WH, Cho JW, Martinez-Chantar ML, Perez-Fernandez R, López M, Dieguez C, Mato JM, Millet O, Coppari R, Woodhoo A, Fruhbeck G, Nogueiras R. Gonzalez-Rellan MJ, et al. Among authors: muller td. Nat Commun. 2021 Aug 20;12(1):5068. doi: 10.1038/s41467-021-25390-0. Nat Commun. 2021. PMID: 34417460 Free PMC article.
The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.
Müller TD, Müller A, Yi CX, Habegger KM, Meyer CW, Gaylinn BD, Finan B, Heppner K, Trivedi C, Bielohuby M, Abplanalp W, Meyer F, Piechowski CL, Pratzka J, Stemmer K, Holland J, Hembree J, Bhardwaj N, Raver C, Ottaway N, Krishna R, Sah R, Sallee FR, Woods SC, Perez-Tilve D, Bidlingmaier M, Thorner MO, Krude H, Smiley D, DiMarchi R, Hofmann S, Pfluger PT, Kleinau G, Biebermann H, Tschöp MH. Müller TD, et al. Among authors: muller a. Nat Commun. 2013;4:1968. doi: 10.1038/ncomms2968. Nat Commun. 2013. PMID: 23744028 Free PMC article.
Review of novel aspects of the regulation of ghrelin secretion.
Al Massadi O, Lear PV, Muller TD, Lopez M, Dieguez C, Tschop MH, Nogueiras R. Al Massadi O, et al. Among authors: muller td. Curr Drug Metab. 2014;15(4):398-413. doi: 10.2174/1389200215666140505153723. Curr Drug Metab. 2014. PMID: 24813425 Review.
Ghrelin and LEAP-2: Rivals in Energy Metabolism.
Al-Massadi O, Müller T, Tschöp M, Diéguez C, Nogueiras R. Al-Massadi O, et al. Trends Pharmacol Sci. 2018 Aug;39(8):685-694. doi: 10.1016/j.tips.2018.06.004. Epub 2018 Jun 29. Trends Pharmacol Sci. 2018. PMID: 30037389 Review.
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.
Clemmensen C, Jall S, Kleinert M, Quarta C, Gruber T, Reber J, Sachs S, Fischer K, Feuchtinger A, Karlas A, Simonds SE, Grandl G, Loher D, Sanchez-Quant E, Keipert S, Jastroch M, Hofmann SM, Nascimento EBM, Schrauwen P, Ntziachristos V, Cowley MA, Finan B, Müller TD, Tschöp MH. Clemmensen C, et al. Among authors: muller td. Nat Commun. 2018 Oct 23;9(1):4304. doi: 10.1038/s41467-018-06769-y. Nat Commun. 2018. PMID: 30353008 Free PMC article.
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD. Fischer K, et al. Among authors: muller td. Nat Commun. 2020 May 8;11(1):2306. doi: 10.1038/s41467-020-16230-8. Nat Commun. 2020. PMID: 32385399 Free PMC article.
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.
Seitz S, Kwon Y, Hartleben G, Jülg J, Sekar R, Krahmer N, Najafi B, Loft A, Gancheva S, Stemmer K, Feuchtinger A, Hrabe de Angelis M, Müller TD, Mann M, Blüher M, Roden M, Berriel Diaz M, Behrends C, Gilleron J, Herzig S, Zeigerer A. Seitz S, et al. Among authors: muller td. Nat Metab. 2019 Oct;1(10):1009-1026. doi: 10.1038/s42255-019-0124-x. Epub 2019 Oct 14. Nat Metab. 2019. PMID: 32694843
Glucagon's Metabolic Action in Health and Disease.
Zeigerer A, Sekar R, Kleinert M, Nason S, Habegger KM, Müller TD. Zeigerer A, et al. Among authors: muller td. Compr Physiol. 2021 Apr 1;11(2):1759-1783. doi: 10.1002/cphy.c200013. Compr Physiol. 2021. PMID: 33792899 Free PMC article.
193 results