Müller R - Search Results

1

Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA.

Fathalla RK, Fröhner W, Bader CD, Fischer PD, Dahlem C, Chatterjee D, Mathea S, Kiemer AK, Arthanari H, Müller R, Abdel-Halim M, Ducho C, Engel M. Fathalla RK, et al. Among authors: muller r. J Med Chem. 2022 Nov 10;65(21):14740-14763. doi: 10.1021/acs.jmedchem.2c01275. Epub 2022 Oct 21. J Med Chem. 2022. PMID: 36269107 Free PMC article.

2

Structure optimization of 2-benzamidobenzoic acids as PqsD inhibitors for Pseudomonas aeruginosa infections and elucidation of binding mode by SPR, STD NMR, and molecular docking.

Weidel E, de Jong JC, Brengel C, Storz MP, Braunshausen A, Negri M, Plaza A, Steinbach A, Müller R, Hartmann RW. Weidel E, et al. Among authors: muller r. J Med Chem. 2013 Aug 8;56(15):6146-55. doi: 10.1021/jm4006302. Epub 2013 Jul 19. J Med Chem. 2013. PMID: 23834469

3

Combining in silico and biophysical methods for the development of Pseudomonas aeruginosa quorum sensing inhibitors: an alternative approach for structure-based drug design.

Sahner JH, Brengel C, Storz MP, Groh M, Plaza A, Müller R, Hartmann RW. Sahner JH, et al. Among authors: muller r. J Med Chem. 2013 Nov 14;56(21):8656-64. doi: 10.1021/jm401102e. Epub 2013 Oct 18. J Med Chem. 2013. PMID: 24083807

4

Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis.

Simon Y, Kessler SM, Gemperlein K, Bohle RM, Müller R, Haybaeck J, Kiemer AK. Simon Y, et al. Among authors: muller r. World J Gastroenterol. 2014 Dec 21;20(47):17839-50. doi: 10.3748/wjg.v20.i47.17839. World J Gastroenterol. 2014. PMID: 25548482 Free PMC article.

5

Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease.

Fengler VH, Macheiner T, Kessler SM, Czepukojc B, Gemperlein K, Müller R, Kiemer AK, Magnes C, Haybaeck J, Lackner C, Sargsyan K. Fengler VH, et al. Among authors: muller r. PLoS One. 2016 May 11;11(5):e0155163. doi: 10.1371/journal.pone.0155163. eCollection 2016. PLoS One. 2016. PMID: 27167736 Free PMC article.

6

Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation.

Kessler SM, Laggai S, Van Wonterg E, Gemperlein K, Müller R, Haybaeck J, Vandenbroucke RE, Ogris M, Libert C, Kiemer AK. Kessler SM, et al. Among authors: muller r. Front Physiol. 2016 Apr 25;7:147. doi: 10.3389/fphys.2016.00147. eCollection 2016. Front Physiol. 2016. PMID: 27199763 Free PMC article.

7

Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies.

Maurer CK, Fruth M, Empting M, Avrutina O, Hoßmann J, Nadmid S, Gorges J, Herrmann J, Kazmaier U, Dersch P, Müller R, Hartmann RW. Maurer CK, et al. Among authors: muller r. Future Med Chem. 2016 Jun;8(9):931-47. doi: 10.4155/fmc-2016-0033. Epub 2016 Jun 2. Future Med Chem. 2016. PMID: 27253623

8

Corrigendum: Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation.

Kessler SM, Laggai S, Van Wonterghem E, Gemperlein K, Müller R, Haybaeck J, Vandenbroucke RE, Ogris M, Libert C, Kiemer AK. Kessler SM, et al. Among authors: muller r. Front Physiol. 2016 Jul 29;7:328. doi: 10.3389/fphys.2016.00328. eCollection 2016. Front Physiol. 2016. PMID: 27489546 Free PMC article.

9

Concepts and Methods to Access Novel Antibiotics from Actinomycetes.

Hug JJ, Bader CD, Remškar M, Cirnski K, Müller R. Hug JJ, et al. Among authors: muller r. Antibiotics (Basel). 2018 May 22;7(2):44. doi: 10.3390/antibiotics7020044. Antibiotics (Basel). 2018. PMID: 29789481 Free PMC article. Review.

10

Engineering Atypical Tetracycline Formation in Amycolatopsis sulphurea for the Production of Modified Chelocardin Antibiotics.

Lukežič T, Fayad AA, Bader C, Harmrolfs K, Bartuli J, Groß S, Lešnik U, Hennessen F, Herrmann J, Pikl Š, Petković H, Müller R. Lukežič T, et al. Among authors: muller r. ACS Chem Biol. 2019 Mar 15;14(3):468-477. doi: 10.1021/acschembio.8b01125. Epub 2019 Feb 12. ACS Chem Biol. 2019. PMID: 30747520

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