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LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis.
Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefanczyk S, Lindner C, Oswald B, Bernhard R, Hähnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, Müller P, Bajoghli B, Skokowa J. Morishima T, et al. Among authors: muller p. Blood. 2019 Oct 3;134(14):1159-1175. doi: 10.1182/blood.2019000095. Epub 2019 Jul 31. Blood. 2019. PMID: 31366618 Free PMC article.
Design of novel granulopoietic proteins by topological rescaffolding.
Hernandez Alvarez B, Skokowa J, Coles M, Mir P, Nasri M, Maksymenko K, Weidmann L, Rogers KW, Welte K, Lupas AN, Müller P, ElGamacy M. Hernandez Alvarez B, et al. Among authors: muller p. PLoS Biol. 2020 Dec 22;18(12):e3000919. doi: 10.1371/journal.pbio.3000919. eCollection 2020 Dec. PLoS Biol. 2020. PMID: 33351791 Free PMC article.
A topological refactoring design strategy yields highly stable granulopoietic proteins.
Skokowa J, Hernandez Alvarez B, Coles M, Ritter M, Nasri M, Haaf J, Aghaallaei N, Xu Y, Mir P, Krahl AC, Rogers KW, Maksymenko K, Bajoghli B, Welte K, Lupas AN, Müller P, ElGamacy M. Skokowa J, et al. Among authors: muller p. Nat Commun. 2022 May 26;13(1):2948. doi: 10.1038/s41467-022-30157-2. Nat Commun. 2022. PMID: 35618709 Free PMC article.
The design of functional proteins using tensorized energy calculations.
Maksymenko K, Maurer A, Aghaallaei N, Barry C, Borbarán-Bravo N, Ullrich T, Dijkstra TMH, Hernandez Alvarez B, Müller P, Lupas AN, Skokowa J, ElGamacy M. Maksymenko K, et al. Among authors: muller p. Cell Rep Methods. 2023 Aug 15;3(8):100560. doi: 10.1016/j.crmeth.2023.100560. eCollection 2023 Aug 28. Cell Rep Methods. 2023. PMID: 37671023 Free PMC article.
A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways.
Piragyte I, Clapes T, Polyzou A, Klein Geltink RI, Lefkopoulos S, Yin N, Cauchy P, Curtis JD, Klaeylé L, Langa X, Beckmann CCA, Wlodarski MW, Müller P, Van Essen D, Rambold A, Kapp FG, Mione M, Buescher JM, Pearce EL, Polyzos A, Trompouki E. Piragyte I, et al. Among authors: muller p. Nat Commun. 2018 Aug 6;9(1):3090. doi: 10.1038/s41467-018-05311-4. Nat Commun. 2018. PMID: 30082823 Free PMC article.
Tuning Protein Diffusivity with Membrane Tethers.
Mörsdorf D, Müller P. Mörsdorf D, et al. Among authors: muller p. Biochemistry. 2019 Jan 22;58(3):177-181. doi: 10.1021/acs.biochem.8b01150. Epub 2018 Dec 24. Biochemistry. 2019. PMID: 30562001 Free PMC article.
3,659 results