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Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription.
Paiva I, Cellai L, Meriaux C, Poncelet L, Nebie O, Saliou JM, Lacoste AS, Papegaey A, Drobecq H, Le Gras S, Schneider M, Malik EM, Müller CE, Faivre E, Carvalho K, Gomez-Murcia V, Vieau D, Thiroux B, Eddarkaoui S, Lebouvier T, Schueller E, Tzeplaeff L, Grgurina I, Seguin J, Stauber J, Lopes LV, Buée L, Buée-Scherrer V, Cunha RA, Ait-Belkacem R, Sergeant N, Annicotte JS, Boutillier AL, Blum D. Paiva I, et al. Among authors: muller ce. J Clin Invest. 2022 Jun 15;132(12):e149371. doi: 10.1172/JCI149371. J Clin Invest. 2022. PMID: 35536645 Free PMC article.
Adenosine receptor antagonists including caffeine alter fetal brain development in mice.
Silva CG, Métin C, Fazeli W, Machado NJ, Darmopil S, Launay PS, Ghestem A, Nesa MP, Bassot E, Szabó E, Baqi Y, Müller CE, Tomé AR, Ivanov A, Isbrandt D, Zilberter Y, Cunha RA, Esclapez M, Bernard C. Silva CG, et al. Among authors: muller ce. Sci Transl Med. 2013 Aug 7;5(197):197ra104. doi: 10.1126/scitranslmed.3006258. Sci Transl Med. 2013. PMID: 23926202 Free article.
A2A adenosine receptor deletion is protective in a mouse model of Tauopathy.
Laurent C, Burnouf S, Ferry B, Batalha VL, Coelho JE, Baqi Y, Malik E, Mariciniak E, Parrot S, Van der Jeugd A, Faivre E, Flaten V, Ledent C, D'Hooge R, Sergeant N, Hamdane M, Humez S, Müller CE, Lopes LV, Buée L, Blum D. Laurent C, et al. Among authors: muller ce. Mol Psychiatry. 2016 Jan;21(1):97-107. doi: 10.1038/mp.2014.151. Epub 2014 Dec 2. Mol Psychiatry. 2016. PMID: 25450226
Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress.
Kaster MP, Machado NJ, Silva HB, Nunes A, Ardais AP, Santana M, Baqi Y, Müller CE, Rodrigues AL, Porciúncula LO, Chen JF, Tomé ÂR, Agostinho P, Canas PM, Cunha RA. Kaster MP, et al. Among authors: muller ce. Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7833-8. doi: 10.1073/pnas.1423088112. Epub 2015 Jun 8. Proc Natl Acad Sci U S A. 2015. PMID: 26056314 Free PMC article.
551 results