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EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation.
Pearson JS, Giogha C, Mühlen S, Nachbur U, Pham CL, Zhang Y, Hildebrand JM, Oates CV, Lung TW, Ingle D, Dagley LF, Bankovacki A, Petrie EJ, Schroeder GN, Crepin VF, Frankel G, Masters SL, Vince J, Murphy JM, Sunde M, Webb AI, Silke J, Hartland EL. Pearson JS, et al. Among authors: muhlen s. Nat Microbiol. 2017 Jan 13;2:16258. doi: 10.1038/nmicrobiol.2016.258. Nat Microbiol. 2017. PMID: 28085133 Free PMC article.
An RNA thermometer dictates production of a secreted bacterial toxin.
Twittenhoff C, Heroven AK, Mühlen S, Dersch P, Narberhaus F. Twittenhoff C, et al. Among authors: muhlen s. PLoS Pathog. 2020 Jan 17;16(1):e1008184. doi: 10.1371/journal.ppat.1008184. eCollection 2020 Jan. PLoS Pathog. 2020. PMID: 31951643 Free PMC article.
34 results