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Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK.
Bustamante-Barrientos FA, Méndez-Ruette M, Molina L, Koning T, Ehrenfeld P, González CB, Wyneken U, Henzi R, Bátiz LF. Bustamante-Barrientos FA, et al. Among authors: mendez ruette m. Front Cell Dev Biol. 2023 Apr 11;11:1061777. doi: 10.3389/fcell.2023.1061777. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37113766 Free PMC article.
Behavioral and Molecular Responses to Exogenous Cannabinoids During Pentylenetetrazol-Induced Convulsions in Male and Female Rats.
Zirotti Rosenberg A, Méndez-Ruette M, Gorziglia M, Alzerreca B, Cabello J, Kaufmann S, Rambousek L, Iturriaga Jofré A, Wyneken U, Lafourcade CA. Zirotti Rosenberg A, et al. Among authors: mendez ruette m. Front Mol Neurosci. 2022 Aug 9;15:868583. doi: 10.3389/fnmol.2022.868583. eCollection 2022. Front Mol Neurosci. 2022. PMID: 36147210 Free PMC article.
The Role of the Rodent Insula in Anxiety.
Méndez-Ruette M, Linsambarth S, Moraga-Amaro R, Quintana-Donoso D, Méndez L, Tamburini G, Cornejo F, Torres RF, Stehberg J. Méndez-Ruette M, et al. Front Physiol. 2019 Mar 29;10:330. doi: 10.3389/fphys.2019.00330. eCollection 2019. Front Physiol. 2019. PMID: 30984021 Free PMC article.
Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons.
Arredondo C, Cefaliello C, Dyrda A, Jury N, Martinez P, Díaz I, Amaro A, Tran H, Morales D, Pertusa M, Stoica L, Fritz E, Corvalán D, Abarzúa S, Méndez-Ruette M, Fernández P, Rojas F, Kumar MS, Aguilar R, Almeida S, Weiss A, Bustos FJ, González-Nilo F, Otero C, Tevy MF, Bosco DA, Sáez JC, Kähne T, Gao FB, Berry JD, Nicholson K, Sena-Esteves M, Madrid R, Varela D, Montecino M, Brown RH, van Zundert B. Arredondo C, et al. Among authors: mendez ruette m. Neuron. 2022 May 18;110(10):1656-1670.e12. doi: 10.1016/j.neuron.2022.02.010. Epub 2022 Mar 10. Neuron. 2022. PMID: 35276083 Free PMC article.
Sumoylation in astrocytes induces changes in the proteome of the derived small extracellular vesicles which change protein synthesis and dendrite morphology in target neurons.
Fernandez A, Corvalan K, Santis O, Mendez-Ruette M, Caviedes A, Pizarro M, Gomez MT, Batiz LF, Landgraf P, Kahne T, Rojas-Fernandez A, Wyneken U. Fernandez A, et al. Among authors: mendez ruette m. Brain Res. 2024 Jan 15;1823:148679. doi: 10.1016/j.brainres.2023.148679. Epub 2023 Nov 14. Brain Res. 2024. PMID: 37972846