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The presence of the 1068 G>A variant of P2X7 receptors is associated to an increase in IL-1Ra levels, insulin secretion and pancreatic β-cell function but not with glycemic control in type 2 diabetes patients.
Uresti-Rivera EE, García-Jacobo RE, Méndez-Cabañas JA, Gaytan-Medina LE, Cortez-Espinosa N, Portales-Pérez DP, González-Amaro R, Enciso-Moreno JA, García-Hernández MH. Uresti-Rivera EE, et al. Among authors: mendez cabanas ja. Gene. 2018 Apr 30;652:1-6. doi: 10.1016/j.gene.2018.01.084. Epub 2018 Feb 6. Gene. 2018. PMID: 29425823