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New route to the 5-((arylthio- and heteroarylthio)methylene)-3-(2,2,2-trifluoroethyl)-furan-2(5H)-ones--key intermediates in the synthesis of 4-aminoquinoline γ-lactams as potent antimalarial compounds.
Kanishchev OS, Lavoignat A, Picot S, Médebielle M, Bouillon JP. Kanishchev OS, et al. Among authors: medebielle m. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6167-71. doi: 10.1016/j.bmcl.2013.08.108. Epub 2013 Sep 7. Bioorg Med Chem Lett. 2013. PMID: 24080459
Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials.
Chopin N, Bosson J, Iikawa S, Picot S, Bienvenu AL, Lavoignat A, Bonnot G, Riou M, Beaugé C, Guillory V, Biot C, Pilet G, Chessé M, Davioud-Charvet E, Elhabiri M, Bouillon JP, Médebielle M. Chopin N, et al. Among authors: medebielle m. Eur J Med Chem. 2022 Dec 5;243:114735. doi: 10.1016/j.ejmech.2022.114735. Epub 2022 Sep 12. Eur J Med Chem. 2022. PMID: 36122550 Free article.
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