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Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
Matovu E, Stewart ML, Geiser F, Brun R, Mäser P, Wallace LJ, Burchmore RJ, Enyaru JC, Barrett MP, Kaminsky R, Seebeck T, de Koning HP. Matovu E, et al. Among authors: maser p. Eukaryot Cell. 2003 Oct;2(5):1003-8. doi: 10.1128/EC.2.5.1003-1008.2003. Eukaryot Cell. 2003. PMID: 14555482 Free PMC article.
The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes.
Teka IA, Kazibwe AJ, El-Sabbagh N, Al-Salabi MI, Ward CP, Eze AA, Munday JC, Mäser P, Matovu E, Barrett MP, de Koning HP. Teka IA, et al. Among authors: maser p. Mol Pharmacol. 2011 Jul;80(1):110-6. doi: 10.1124/mol.111.071555. Epub 2011 Mar 24. Mol Pharmacol. 2011. PMID: 21436312 Free PMC article.
Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.
Munday JC, Eze AA, Baker N, Glover L, Clucas C, Aguinaga Andrés D, Natto MJ, Teka IA, McDonald J, Lee RS, Graf FE, Ludin P, Burchmore RJ, Turner CM, Tait A, MacLeod A, Mäser P, Barrett MP, Horn D, De Koning HP. Munday JC, et al. Among authors: maser p. J Antimicrob Chemother. 2014 Mar;69(3):651-63. doi: 10.1093/jac/dkt442. Epub 2013 Nov 13. J Antimicrob Chemother. 2014. PMID: 24235095 Free PMC article.
TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.
Shameer S, Logan-Klumpler FJ, Vinson F, Cottret L, Merlet B, Achcar F, Boshart M, Berriman M, Breitling R, Bringaud F, Bütikofer P, Cattanach AM, Bannerman-Chukualim B, Creek DJ, Crouch K, de Koning HP, Denise H, Ebikeme C, Fairlamb AH, Ferguson MA, Ginger ML, Hertz-Fowler C, Kerkhoven EJ, Mäser P, Michels PA, Nayak A, Nes DW, Nolan DP, Olsen C, Silva-Franco F, Smith TK, Taylor MC, Tielens AG, Urbaniak MD, van Hellemond JJ, Vincent IM, Wilkinson SR, Wyllie S, Opperdoes FR, Barrett MP, Jourdan F. Shameer S, et al. Among authors: maser p. Nucleic Acids Res. 2015 Jan;43(Database issue):D637-44. doi: 10.1093/nar/gku944. Epub 2014 Oct 9. Nucleic Acids Res. 2015. PMID: 25300491 Free PMC article.
An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei.
de Macêdo JP, Schumann Burkard G, Niemann M, Barrett MP, Vial H, Mäser P, Roditi I, Schneider A, Bütikofer P. de Macêdo JP, et al. Among authors: maser p. PLoS Pathog. 2015 May 6;11(5):e1004875. doi: 10.1371/journal.ppat.1004875. eCollection 2015 May. PLoS Pathog. 2015. PMID: 25946070 Free PMC article.
Drug Discovery for Kinetoplastid Diseases: Future Directions.
Rao SPS, Barrett MP, Dranoff G, Faraday CJ, Gimpelewicz CR, Hailu A, Jones CL, Kelly JM, Lazdins-Helds JK, Mäser P, Mengel J, Mottram JC, Mowbray CE, Sacks DL, Scott P, Späth GF, Tarleton RL, Spector JM, Diagana TT. Rao SPS, et al. Among authors: maser p. ACS Infect Dis. 2019 Feb 8;5(2):152-157. doi: 10.1021/acsinfecdis.8b00298. Epub 2018 Dec 13. ACS Infect Dis. 2019. PMID: 30543391 Free article.
157 results