Lynn AM - Search Results

1

Identifying the natural polyphenol catechin as a multi-targeted agent against SARS-CoV-2 for the plausible therapy of COVID-19: an integrated computational approach.

Mishra CB, Pandey P, Sharma RD, Malik MZ, Mongre RK, Lynn AM, Prasad R, Jeon R, Prakash A. Mishra CB, et al. Among authors: lynn am. Brief Bioinform. 2021 Mar 22;22(2):1346-1360. doi: 10.1093/bib/bbaa378. Brief Bioinform. 2021. PMID: 33386025 Free PMC article.

2

Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump.

Jha S, Karnani N, Lynn AM, Prasad R. Jha S, et al. Among authors: lynn am. Biochem Biophys Res Commun. 2003 Oct 24;310(3):869-75. doi: 10.1016/j.bbrc.2003.09.094. Biochem Biophys Res Commun. 2003. PMID: 14550284

3

High temperature unfolding of Bacillus anthracis amidase-03 by molecular dynamics simulations.

Sharma RD, Lynn AM, Sharma PK, Rajnee, Jawaid S. Sharma RD, et al. Among authors: lynn am. Bioinformation. 2009 Jul 27;3(10):430-4. doi: 10.6026/97320630003430. Bioinformation. 2009. PMID: 19759865 Free PMC article.

4

Rational mutational analysis of a multidrug MFS transporter CaMdr1p of Candida albicans by employing a membrane environment based computational approach.

Kapoor K, Rehan M, Kaushiki A, Pasrija R, Lynn AM, Prasad R. Kapoor K, et al. Among authors: lynn am. PLoS Comput Biol. 2009 Dec;5(12):e1000624. doi: 10.1371/journal.pcbi.1000624. Epub 2009 Dec 24. PLoS Comput Biol. 2009. PMID: 20041202 Free PMC article.

5

Employing information theoretic measures and mutagenesis to identify residues critical for drug-proton antiport function in Mdr1p of Candida albicans.

Kapoor K, Rehan M, Lynn AM, Prasad R. Kapoor K, et al. Among authors: lynn am. PLoS One. 2010 Jun 10;5(6):e11041. doi: 10.1371/journal.pone.0011041. PLoS One. 2010. PMID: 20548793 Free PMC article.

6

A modeled structure for amidase-03 from Bacillus anthracis.

Sharma RD, Goswami N, Lynn AM, Rajnee, Sharma PK, Jawaid S. Sharma RD, et al. Among authors: lynn am. Bioinformation. 2009 Dec 31;4(6):242-4. doi: 10.6026/97320630004242. Bioinformation. 2009. PMID: 20975917 Free PMC article.

7

A key structural domain of the Candida albicans Mdr1 protein.

Mandal A, Kumar A, Singh A, Lynn AM, Kapoor K, Prasad R. Mandal A, et al. Among authors: lynn am. Biochem J. 2012 Aug 1;445(3):313-22. doi: 10.1042/BJ20120190. Biochem J. 2012. PMID: 22587419

8

Rationally designed transmembrane peptide mimics of the multidrug transporter protein Cdr1 act as antagonists to selectively block drug efflux and chemosensitize azole-resistant clinical isolates of Candida albicans.

Maurya IK, Thota CK, Verma SD, Sharma J, Rawal MK, Ravikumar B, Sen S, Chauhan N, Lynn AM, Chauhan VS, Prasad R. Maurya IK, et al. Among authors: lynn am. J Biol Chem. 2013 Jun 7;288(23):16775-16787. doi: 10.1074/jbc.M113.467159. Epub 2013 Apr 16. J Biol Chem. 2013. PMID: 23592791 Free PMC article. Retracted.

9

Insight into pleiotropic drug resistance ATP-binding cassette pump drug transport through mutagenesis of Cdr1p transmembrane domains.

Rawal MK, Khan MF, Kapoor K, Goyal N, Sen S, Saxena AK, Lynn AM, Tyndall JD, Monk BC, Cannon RD, Komath SS, Prasad R. Rawal MK, et al. Among authors: lynn am. J Biol Chem. 2013 Aug 23;288(34):24480-93. doi: 10.1074/jbc.M113.488353. Epub 2013 Jul 3. J Biol Chem. 2013. PMID: 23824183 Free PMC article.

10

High temperature unfolding of a truncated hemoglobin by molecular dynamics simulation.

Sharma RD, Kanwal R, Lynn AM, Singh P, Pasha ST, Fatma T, Jawaid S. Sharma RD, et al. Among authors: lynn am. J Mol Model. 2013 Sep;19(9):3993-4002. doi: 10.1007/s00894-013-1919-4. Epub 2013 Jul 10. J Mol Model. 2013. PMID: 23839248

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