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Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins.
Ali YM, Ferrari M, Lynch NJ, Yaseen S, Dudler T, Gragerov S, Demopulos G, Heeney JL, Schwaeble WJ. Ali YM, et al. Among authors: lynch nj. Front Immunol. 2021 Jul 5;12:714511. doi: 10.3389/fimmu.2021.714511. eCollection 2021. Front Immunol. 2021. PMID: 34290717 Free PMC article.
The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3.
Stover C, Endo Y, Takahashi M, Lynch NJ, Constantinescu C, Vorup-Jensen T, Thiel S, Friedl H, Hankeln T, Hall R, Gregory S, Fujita T, Schwaeble W. Stover C, et al. Among authors: lynch nj. Genes Immun. 2001 May;2(3):119-27. doi: 10.1038/sj.gene.6363745. Genes Immun. 2001. PMID: 11426320
51 results