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Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut.
Lynch JP, González-Prieto C, Reeves AZ, Bae S, Powale U, Godbole NP, Tremblay JM, Schmidt FI, Ploegh HL, Kansra V, Glickman JN, Leong JM, Shoemaker CB, Garrett WS, Lesser CF. Lynch JP, et al. Cell Host Microbe. 2023 Apr 12;31(4):634-649.e8. doi: 10.1016/j.chom.2023.03.007. Epub 2023 Mar 31. Cell Host Microbe. 2023. PMID: 37003258 Free PMC article.
A host metabolite promotes Salmonella survival.
Lynch JP, Lesser CF. Lynch JP, et al. Science. 2021 Jan 22;371(6527):344-345. doi: 10.1126/science.abf8414. Science. 2021. PMID: 33479138 No abstract available.
Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report.
Cable J, Leonard JN, Lu TK, Xie Z, Chang MW, Fernández LÁ, Lora JM, Kaufman HL, Quintana FJ, Geiger R, F Lesser C, Lynch JP, Hava DL, Cornish VW, Lee GK, DiAndreth B, Fero M, Srivastava R, De Coster T, Roybal KT, Rackham OJL, Kiani S, Zhu I, Hernandez-Lopez RA, Guo T, Chen WCW. Cable J, et al. Among authors: lynch jp. Ann N Y Acad Sci. 2021 Dec;1506(1):98-117. doi: 10.1111/nyas.14710. Epub 2021 Nov 16. Ann N Y Acad Sci. 2021. PMID: 34786712 Review.
610 results