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CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study.
Lancet Oncol. 2021 Jan;22(1):118-131. doi: 10.1016/S1470-2045(20)30532-5.
Lancet Oncol. 2021.
PMID: 33387490
Clinical Trial.
Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial.
Padrón LJ, Maurer DM, O'Hara MH, O'Reilly EM, Wolff RA, Wainberg ZA, Ko AH, Fisher G, Rahma O, Lyman JP, Cabanski CR, Yu JX, Pfeiffer SM, Spasic M, Xu J, Gherardini PF, Karakunnel J, Mick R, Alanio C, Byrne KT, Hollmann TJ, Moore JS, Jones DD, Tognetti M, Chen RO, Yang X, Salvador L, Wherry EJ, Dugan U, O'Donnell-Tormey J, Butterfield LH, Hubbard-Lucey VM, Ibrahim R, Fairchild J, Bucktrout S, LaVallee TM, Vonderheide RH.
Padrón LJ, et al. Among authors: lyman jp.
Nat Med. 2022 Jun;28(6):1167-1177. doi: 10.1038/s41591-022-01829-9. Epub 2022 Jun 3.
Nat Med. 2022.
PMID: 35662283
Free PMC article.
Clinical Trial.
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The Italian Network for Tumor Bio-Immunotherapy (NIBIT) Foundation: ongoing and prospective activities in immuno-oncology.
Di Giacomo AM, Covre A, Giacobini G, Ibrahim R, Lyman J, Natali PG, Maio M.
Di Giacomo AM, et al.
Cancer Immunol Immunother. 2019 Jan;68(1):143-150. doi: 10.1007/s00262-018-2286-x. Epub 2018 Dec 18.
Cancer Immunol Immunother. 2019.
PMID: 30564888
Free PMC article.
Review.
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Prognostic Impact of 21-Gene Recurrence Score in Patients With Stage IV Breast Cancer: TBCRC 013.
King TA, Lyman JP, Gonen M, Voci A, De Brot M, Boafo C, Sing AP, Hwang ES, Alvarado MD, Liu MC, Boughey JC, McGuire KP, Van Poznak CH, Jacobs LK, Meszoely IM, Krontiras H, Babiera GV, Norton L, Morrow M, Hudis CA.
King TA, et al. Among authors: lyman jp.
J Clin Oncol. 2016 Jul 10;34(20):2359-65. doi: 10.1200/JCO.2015.63.1960. Epub 2016 Mar 21.
J Clin Oncol. 2016.
PMID: 27001590
Free PMC article.
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Novel methylated biomarkers and a robust assay to detect circulating tumor DNA in metastatic breast cancer.
Fackler MJ, Lopez Bujanda Z, Umbricht C, Teo WW, Cho S, Zhang Z, Visvanathan K, Jeter S, Argani P, Wang C, Lyman JP, de Brot M, Ingle JN, Boughey J, McGuire K, King TA, Carey LA, Cope L, Wolff AC, Sukumar S.
Fackler MJ, et al. Among authors: lyman jp.
Cancer Res. 2014 Apr 15;74(8):2160-70. doi: 10.1158/0008-5472.CAN-13-3392.
Cancer Res. 2014.
PMID: 24737128
Free PMC article.
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RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch.
Walsh LA, Roy DM, Reyngold M, Giri D, Snyder A, Turcan S, Badwe CR, Lyman J, Bromberg J, King TA, Chan TA.
Walsh LA, et al.
Oncogene. 2015 Apr 23;34(17):2189-203. doi: 10.1038/onc.2014.175. Epub 2014 Jun 16.
Oncogene. 2015.
PMID: 24931164
Free PMC article.
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Consequences to the patient in the event of hydraulic unit failure.
Smith V, Verhey L, Jones E, Lyman J.
Smith V, et al.
Stereotact Funct Neurosurg. 1993;61 Suppl 1:173-7. doi: 10.1159/000100671.
Stereotact Funct Neurosurg. 1993.
PMID: 8115749
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Stereotactic heavy-particle irradiation of intracranial arteriovenous malformations.
Hosobuchi Y, Fabricant J, Lyman J.
Hosobuchi Y, et al.
Appl Neurophysiol. 1987;50(1-6):248-52.
Appl Neurophysiol. 1987.
PMID: 3329856
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