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Page 1
Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage.
Petropoulos M, Champeris Tsaniras S, Nikou S, Maxouri S, Dionellis VS, Kalogeropoulou A, Karamichali A, Ioannidis K, Danalatos IR, Obst M, Naumann R, Delinasios GJ, Gorgoulis VG, Roukos V, Anastassiadis K, Halazonetis TD, Bravou V, Lygerou Z, Taraviras S. Petropoulos M, et al. Among authors: lygerou z. J Pathol. 2023 Jan;259(1):10-20. doi: 10.1002/path.6017. Epub 2022 Nov 9. J Pathol. 2023. PMID: 36210634
Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional control over hCdt1.
Karakaidos P, Taraviras S, Vassiliou LV, Zacharatos P, Kastrinakis NG, Kougiou D, Kouloukoussa M, Nishitani H, Papavassiliou AG, Lygerou Z, Gorgoulis VG. Karakaidos P, et al. Among authors: lygerou z. Am J Pathol. 2004 Oct;165(4):1351-65. doi: 10.1016/S0002-9440(10)63393-7. Am J Pathol. 2004. PMID: 15466399 Free PMC article.
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.
Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Nakayama KI, Nakayama K, Fujita M, Lygerou Z, Nishimoto T. Nishitani H, et al. Among authors: lygerou z. EMBO J. 2006 Mar 8;25(5):1126-36. doi: 10.1038/sj.emboj.7601002. Epub 2006 Feb 16. EMBO J. 2006. PMID: 16482215 Free PMC article.
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior.
Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, Kotsinas A, Nahum O, Zoumpourlis V, Kouloukoussa M, Lygerou Z, Taraviras S, Kittas C, Bartkova J, Papavassiliou AG, Bartek J, Halazonetis TD, Gorgoulis VG. Liontos M, et al. Among authors: lygerou z. Cancer Res. 2007 Nov 15;67(22):10899-909. doi: 10.1158/0008-5472.CAN-07-2837. Cancer Res. 2007. PMID: 18006835
Life without geminin.
Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S. Karamitros D, et al. Among authors: lygerou z. Cell Cycle. 2010 Aug 15;9(16):3181-5. doi: 10.4161/cc.9.16.12554. Epub 2010 Aug 28. Cell Cycle. 2010. PMID: 20697201 Free PMC article.
90 results