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Page 1
53BP1-mediated recruitment of RASSF1A to ribosomal DNA breaks promotes local ATM signaling.
Tsaridou S, Velimezi G, Willenbrock F, Chatzifrangkeskou M, Elsayed W, Panagopoulos A, Karamitros D, Gorgoulis V, Lygerou Z, Roukos V, O'Neill E, Pefani DE. Tsaridou S, et al. Among authors: lygerou z. EMBO Rep. 2022 Aug 3;23(8):e54483. doi: 10.15252/embr.202154483. Epub 2022 Jun 27. EMBO Rep. 2022. PMID: 35758159 Free PMC article.
Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional control over hCdt1.
Karakaidos P, Taraviras S, Vassiliou LV, Zacharatos P, Kastrinakis NG, Kougiou D, Kouloukoussa M, Nishitani H, Papavassiliou AG, Lygerou Z, Gorgoulis VG. Karakaidos P, et al. Among authors: lygerou z. Am J Pathol. 2004 Oct;165(4):1351-65. doi: 10.1016/S0002-9440(10)63393-7. Am J Pathol. 2004. PMID: 15466399 Free PMC article.
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.
Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Nakayama KI, Nakayama K, Fujita M, Lygerou Z, Nishimoto T. Nishitani H, et al. Among authors: lygerou z. EMBO J. 2006 Mar 8;25(5):1126-36. doi: 10.1038/sj.emboj.7601002. Epub 2006 Feb 16. EMBO J. 2006. PMID: 16482215 Free PMC article.
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior.
Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, Kotsinas A, Nahum O, Zoumpourlis V, Kouloukoussa M, Lygerou Z, Taraviras S, Kittas C, Bartkova J, Papavassiliou AG, Bartek J, Halazonetis TD, Gorgoulis VG. Liontos M, et al. Among authors: lygerou z. Cancer Res. 2007 Nov 15;67(22):10899-909. doi: 10.1158/0008-5472.CAN-07-2837. Cancer Res. 2007. PMID: 18006835
Life without geminin.
Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S. Karamitros D, et al. Among authors: lygerou z. Cell Cycle. 2010 Aug 15;9(16):3181-5. doi: 10.4161/cc.9.16.12554. Epub 2010 Aug 28. Cell Cycle. 2010. PMID: 20697201 Free PMC article.
Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage.
Roukos V, Kinkhabwala A, Colombelli J, Kotsantis P, Taraviras S, Nishitani H, Stelzer E, Bastiaens P, Lygerou Z. Roukos V, et al. Among authors: lygerou z. J Cell Sci. 2011 Feb 1;124(Pt 3):422-34. doi: 10.1242/jcs.074229. Epub 2011 Jan 11. J Cell Sci. 2011. PMID: 21224399
Reduced Geminin levels promote cellular senescence.
Iliou MS, Kotantaki P, Karamitros D, Spella M, Taraviras S, Lygerou Z. Iliou MS, et al. Among authors: lygerou z. Mech Ageing Dev. 2013 Jan-Feb;134(1-2):10-23. doi: 10.1016/j.mad.2012.10.001. Epub 2012 Nov 8. Mech Ageing Dev. 2013. PMID: 23142824
90 results