Lv W - Search Results

1

Recent Developments Using Small Molecules to Target RAD51: How to Best Modulate RAD51 for Anticancer Therapy?

Budke B, Lv W, Kozikowski AP, Connell PP. Budke B, et al. Among authors: lv w. ChemMedChem. 2016 Nov 21;11(22):2468-2473. doi: 10.1002/cmdc.201600426. Epub 2016 Oct 26. ChemMedChem. 2016. PMID: 27781374 Free PMC article. Review.

2

Development of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51.

Lv W, Budke B, Pawlowski M, Connell PP, Kozikowski AP. Lv W, et al. J Med Chem. 2016 May 26;59(10):4511-25. doi: 10.1021/acs.jmedchem.5b01762. Epub 2016 Apr 21. J Med Chem. 2016. PMID: 27049177 Free PMC article.

3

Design and Synthesis of (2-(5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)methanamine as a Selective Serotonin 2C Agonist.

Cheng J, Giguere PM, Lv W, Roth BL, Kozikowski AP. Cheng J, et al. Among authors: lv w. Tetrahedron Lett. 2015 Jun 3;56(23):3420-3422. doi: 10.1016/j.tetlet.2015.01.060. Tetrahedron Lett. 2015. PMID: 26120215 Free PMC article.

4

Design and Synthesis of Mercaptoacetamides as Potent, Selective, and Brain Permeable Histone Deacetylase 6 Inhibitors.

Lv W, Zhang G, Barinka C, Eubanks JH, Kozikowski AP. Lv W, et al. ACS Med Chem Lett. 2017 Apr 7;8(5):510-515. doi: 10.1021/acsmedchemlett.7b00012. eCollection 2017 May 11. ACS Med Chem Lett. 2017. PMID: 28523102 Free PMC article.

5

Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents.

Cheng J, Giguère PM, Onajole OK, Lv W, Gaisin A, Gunosewoyo H, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Vistoli G, Wetsel WC, Roth BL, Kozikowski AP. Cheng J, et al. Among authors: lv w. J Med Chem. 2015 Feb 26;58(4):1992-2002. doi: 10.1021/jm5019274. Epub 2015 Feb 10. J Med Chem. 2015. PMID: 25633969 Free PMC article.

6

Development of Tetrahydroindazole-Based Potent and Selective Sigma-2 Receptor Ligands.

Iyamu ID, Lv W, Malik N, Mishra RK, Schiltz GE. Iyamu ID, et al. Among authors: lv w. ChemMedChem. 2019 Jul 3;14(13):1248-1256. doi: 10.1002/cmdc.201900203. Epub 2019 Jun 3. ChemMedChem. 2019. PMID: 31071238 Free PMC article.

7

Synthesis of 3-(3-aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazines that have antibacterial activity and also inhibit inorganic pyrophosphatase.

Lv W, Banerjee B, Molland KL, Seleem MN, Ghafoor A, Hamed MI, Wan B, Franzblau SG, Mesecar AD, Cushman M. Lv W, et al. Bioorg Med Chem. 2014 Jan 1;22(1):406-18. doi: 10.1016/j.bmc.2013.11.011. Epub 2013 Nov 15. Bioorg Med Chem. 2014. PMID: 24315189 Free PMC article.

8

Investigation of the Structure-Activity Relationships of Aza-A-Ring Indenoisoquinoline Topoisomerase I Poisons.

Beck DE, Reddy PV, Lv W, Abdelmalak M, Tender GS, Lopez S, Agama K, Marchand C, Pommier Y, Cushman M. Beck DE, et al. Among authors: lv w. J Med Chem. 2016 Apr 28;59(8):3840-53. doi: 10.1021/acs.jmedchem.6b00003. Epub 2016 Apr 12. J Med Chem. 2016. PMID: 27070999 Free PMC article.

9

Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands.

Iyamu ID, Lv W, Malik N, Mishra RK, Schiltz GE. Iyamu ID, et al. Among authors: lv w. Bioorg Med Chem. 2019 May 1;27(9):1824-1835. doi: 10.1016/j.bmc.2019.03.030. Epub 2019 Mar 16. Bioorg Med Chem. 2019. PMID: 30904383 Free PMC article.

10

In vitro evaluation of potential bitterness-masking terpenoids from the Canada goldenrod (Solidago canadensis).

Li J, Pan L, Fletcher JN, Lv W, Deng Y, Vincent MA, Slack JP, McCluskey TS, Jia Z, Cushman M, Kinghorn AD. Li J, et al. Among authors: lv w. J Nat Prod. 2014 Jul 25;77(7):1739-43. doi: 10.1021/np5001413. Epub 2014 Jul 7. J Nat Prod. 2014. PMID: 24999828

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