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Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model.
Acta Pharmacol Sin. 2023 Nov;44(11):2342-2345. doi: 10.1038/s41401-023-01115-5. Epub 2023 Jul 4.
Acta Pharmacol Sin. 2023.
PMID: 37402996
No abstract available.
A high-fidelity RNA-targeting Cas13 restores paternal Ube3a expression and improves motor functions in Angelman syndrome mice.
Li J, Shen Z, Liu Y, Yan Z, Liu Y, Lin X, Tang J, Lv R, Geng G, Xiong ZQ, Zhou C, Yang H.
Li J, et al.
Mol Ther. 2023 Jul 5;31(7):2286-2295. doi: 10.1016/j.ymthe.2023.02.015. Epub 2023 Feb 18.
Mol Ther. 2023.
PMID: 36805082
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