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Page 1
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
Luc S, Luis TC, Boukarabila H, Macaulay IC, Buza-Vidas N, Bouriez-Jones T, Lutteropp M, Woll PS, Loughran SJ, Mead AJ, Hultquist A, Brown J, Mizukami T, Matsuoka S, Ferry H, Anderson K, Duarte S, Atkinson D, Soneji S, Domanski A, Farley A, Sanjuan-Pla A, Carella C, Patient R, de Bruijn M, Enver T, Nerlov C, Blackburn C, Godin I, Jacobsen SE. Luc S, et al. Among authors: lutteropp m. Nat Immunol. 2012 Feb 19;13(4):412-9. doi: 10.1038/ni.2255. Nat Immunol. 2012. PMID: 22344248 Free PMC article.
Dicer is selectively important for the earliest stages of erythroid development.
Buza-Vidas N, Cismasiu VB, Moore S, Mead AJ, Woll PS, Lutteropp M, Melchiori L, Luc S, Bouriez-Jones T, Atkinson D, O'Carroll D, Jacobsen SE, Nerlov C. Buza-Vidas N, et al. Among authors: lutteropp m. Blood. 2012 Sep 20;120(12):2412-6. doi: 10.1182/blood-2011-10-383653. Epub 2012 Aug 6. Blood. 2012. PMID: 22869792 Free article.
FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
Mead AJ, Kharazi S, Atkinson D, Macaulay I, Pecquet C, Loughran S, Lutteropp M, Woll P, Chowdhury O, Luc S, Buza-Vidas N, Ferry H, Clark SA, Goardon N, Vyas P, Constantinescu SN, Sitnicka E, Nerlov C, Jacobsen SE. Mead AJ, et al. Among authors: lutteropp m. Cell Rep. 2013 Jun 27;3(6):1766-76. doi: 10.1016/j.celrep.2013.04.031. Epub 2013 May 30. Cell Rep. 2013. PMID: 23727242 Free PMC article.
Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells.
Böiers C, Carrelha J, Lutteropp M, Luc S, Green JC, Azzoni E, Woll PS, Mead AJ, Hultquist A, Swiers G, Perdiguero EG, Macaulay IC, Melchiori L, Luis TC, Kharazi S, Bouriez-Jones T, Deng Q, Pontén A, Atkinson D, Jensen CT, Sitnicka E, Geissmann F, Godin I, Sandberg R, de Bruijn MF, Jacobsen SE. Böiers C, et al. Among authors: lutteropp m. Cell Stem Cell. 2013 Nov 7;13(5):535-48. doi: 10.1016/j.stem.2013.08.012. Epub 2013 Sep 19. Cell Stem Cell. 2013. PMID: 24054998 Free article.
Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.
Sanjuan-Pla A, Macaulay IC, Jensen CT, Woll PS, Luis TC, Mead A, Moore S, Carella C, Matsuoka S, Bouriez Jones T, Chowdhury O, Stenson L, Lutteropp M, Green JC, Facchini R, Boukarabila H, Grover A, Gambardella A, Thongjuea S, Carrelha J, Tarrant P, Atkinson D, Clark SA, Nerlov C, Jacobsen SE. Sanjuan-Pla A, et al. Among authors: lutteropp m. Nature. 2013 Oct 10;502(7470):232-6. doi: 10.1038/nature12495. Epub 2013 Aug 11. Nature. 2013. PMID: 23934107
Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.
Luis TC, Luc S, Mizukami T, Boukarabila H, Thongjuea S, Woll PS, Azzoni E, Giustacchini A, Lutteropp M, Bouriez-Jones T, Vaidya H, Mead AJ, Atkinson D, Böiers C, Carrelha J, Macaulay IC, Patient R, Geissmann F, Nerlov C, Sandberg R, de Bruijn MFTR, Blackburn CC, Godin I, Jacobsen SEW. Luis TC, et al. Among authors: lutteropp m. Nat Immunol. 2016 Dec;17(12):1424-1435. doi: 10.1038/ni.3576. Epub 2016 Oct 3. Nat Immunol. 2016. PMID: 27695000 Free PMC article.
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.
Mortensen M, Soilleux EJ, Djordjevic G, Tripp R, Lutteropp M, Sadighi-Akha E, Stranks AJ, Glanville J, Knight S, Jacobsen SE, Kranc KR, Simon AK. Mortensen M, et al. Among authors: lutteropp m. J Exp Med. 2011 Mar 14;208(3):455-67. doi: 10.1084/jem.20101145. Epub 2011 Feb 21. J Exp Med. 2011. PMID: 21339326 Free PMC article.
Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option.
Stamm H, Klingler F, Grossjohann EM, Muschhammer J, Vettorazzi E, Heuser M, Mock U, Thol F, Vohwinkel G, Latuske E, Bokemeyer C, Kischel R, Dos Santos C, Stienen S, Friedrich M, Lutteropp M, Nagorsen D, Wellbrock J, Fiedler W. Stamm H, et al. Among authors: lutteropp m. Oncogene. 2018 Sep;37(39):5269-5280. doi: 10.1038/s41388-018-0288-y. Epub 2018 May 31. Oncogene. 2018. PMID: 29855615 Free PMC article.
12 results