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Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture.
Sun J, Singh P, Shami A, Kluza E, Pan M, Djordjevic D, Michaelsen NB, Kennbäck C, van der Wel NN, Orho-Melander M, Nilsson J, Formentini I, Conde-Knape K, Lutgens E, Edsfeldt A, Gonçalves I. Sun J, et al. Among authors: lutgens e. J Am Coll Cardiol. 2023 Jun 13;81(23):2213-2227. doi: 10.1016/j.jacc.2023.04.008. J Am Coll Cardiol. 2023. PMID: 37286250
Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis increasing the risk of cerebrovascular complications.
Dib L, Koneva LA, Edsfeldt A, Zurke YX, Sun J, Nitulescu M, Attar M, Lutgens E, Schmidt S, Lindholm MW, Choudhury RP, Cassimjee I, Lee R, Handa A, Goncalves I, Sansom SN, Monaco C. Dib L, et al. Among authors: lutgens e. Nat Cardiovasc Res. 2023 Jun 26;2(7):656-672. doi: 10.1038/s44161-023-00295-x. Nat Cardiovasc Res. 2023. PMID: 38362263 Free PMC article.
Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification.
Pavlic A, Poelman H, Wasilewski G, Wichapong K, Lux P, Maassen C, Lutgens E, Schurgers LJ, Reutelingsperger CP, Nicolaes GAF. Pavlic A, et al. Among authors: lutgens e. Int J Mol Sci. 2023 Jan 19;24(3):2027. doi: 10.3390/ijms24032027. Int J Mol Sci. 2023. PMID: 36768348 Free PMC article.
Time-restricted feeding attenuates hypercholesterolaemia and atherosclerosis development during circadian disturbance in APOE∗3-Leiden.CETP mice.
In Het Panhuis W, Schönke M, Modder M, Tom HE, Lalai RA, Pronk ACM, Streefland TCM, van Kerkhof LWM, Dollé MET, Depuydt MAC, Bot I, Vos WG, Bosmans LA, van Os BW, Lutgens E, Rensen PCN, Kooijman S. In Het Panhuis W, et al. Among authors: lutgens e. EBioMedicine. 2023 Jul;93:104680. doi: 10.1016/j.ebiom.2023.104680. Epub 2023 Jun 23. EBioMedicine. 2023. PMID: 37356205 Free PMC article.
The IRAK-M death domain: a tale of three surfaces.
Gürkan B, Poelman H, Pereverzeva L, Kruijswijk D, de Vos AF, Groenen AG, Nollet EE, Wichapong K, Lutgens E, van der Poll T, Du J, Wiersinga WJ, Nicolaes GAF, van 't Veer C. Gürkan B, et al. Among authors: lutgens e. Front Mol Biosci. 2024 Jan 10;10:1265455. doi: 10.3389/fmolb.2023.1265455. eCollection 2023. Front Mol Biosci. 2024. PMID: 38268724 Free PMC article.
Uncovering atherosclerotic cardiovascular disease by PET imaging.
Maier A, Teunissen AJP, Nauta SA, Lutgens E, Fayad ZA, van Leent MMT. Maier A, et al. Among authors: lutgens e. Nat Rev Cardiol. 2024 Apr 4. doi: 10.1038/s41569-024-01009-x. Online ahead of print. Nat Rev Cardiol. 2024. PMID: 38575752 Review.
Role of inflammatory signaling pathways involving the CD40-CD40L-TRAF cascade in diabetes and hypertension-insights from animal and human studies.
Strohm L, Daiber A, Ubbens H, Krishnankutty R, Oelze M, Kuntic M, Hahad O, Klein V, Hoefer IE, von Kriegsheim A, Kleinert H, Atzler D, Lurz P, Weber C, Wild PS, Münzel T, Knosalla C, Lutgens E, Daub S. Strohm L, et al. Among authors: lutgens e. Basic Res Cardiol. 2024 Mar 30. doi: 10.1007/s00395-024-01045-1. Online ahead of print. Basic Res Cardiol. 2024. PMID: 38554187
T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.
Vos WG, van Os BW, den Toom M, Beckers L, van Roomen CPAA, van Tiel CM, Mohapatra BC, Band H, Nitz K, Weber C, Atzler D, de Winther MPJ, Bosmans LA, Lutgens E, Seijkens TTP. Vos WG, et al. Among authors: lutgens e. Front Immunol. 2024 Mar 4;15:1297893. doi: 10.3389/fimmu.2024.1297893. eCollection 2024. Front Immunol. 2024. PMID: 38504977 Free PMC article.
240 results