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Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivity.
Cimbro R, Gallant TR, Dolan MA, Guzzo C, Zhang P, Lin Y, Miao H, Van Ryk D, Arthos J, Gorshkova I, Brown PH, Hurt DE, Lusso P. Cimbro R, et al. Among authors: lusso p. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3152-7. doi: 10.1073/pnas.1314718111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24569807 Free PMC article.
Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry.
Cimbro R, Peterson FC, Liu Q, Guzzo C, Zhang P, Miao H, Van Ryk D, Ambroggio X, Hurt DE, De Gioia L, Volkman BF, Dolan MA, Lusso P. Cimbro R, et al. Among authors: lusso p. EBioMedicine. 2016 Aug;10:45-54. doi: 10.1016/j.ebiom.2016.06.037. Epub 2016 Jun 26. EBioMedicine. 2016. PMID: 27389109 Free PMC article.
221 results