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Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.
Pasula S, Cai X, Dong Y, Messa M, McManus J, Chang B, Liu X, Zhu H, Mansat RS, Yoon SJ, Hahn S, Keeling J, Saunders D, Ko G, Knight J, Newton G, Luscinskas F, Sun X, Towner R, Lupu F, Xia L, Cremona O, De Camilli P, Min W, Chen H. Pasula S, et al. Among authors: lupu f. J Clin Invest. 2012 Dec;122(12):4424-38. doi: 10.1172/JCI64537. Epub 2012 Nov 26. J Clin Invest. 2012. PMID: 23187125 Free PMC article.
Motif mimetic of epsin perturbs tumor growth and metastasis.
Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H. Dong Y, et al. Among authors: lupu f. J Clin Invest. 2015 Dec;125(12):4349-64. doi: 10.1172/JCI80349. Epub 2015 Nov 16. J Clin Invest. 2015. PMID: 26571402 Free PMC article.
Motif mimetic of epsin perturbs tumor growth and metastasis.
Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H. Dong Y, et al. Among authors: lupu f. J Clin Invest. 2016 Apr 1;126(4):1607. doi: 10.1172/JCI87344. Epub 2016 Mar 21. J Clin Invest. 2016. PMID: 26999611 Free PMC article. No abstract available.
OKN-007 decreases VEGFR-2 levels in a preclinical GL261 mouse glioma model.
de Souza PC, Smith N, Pody R, He T, Njoku C, Silasi-Mansat R, Lupu F, Meek B, Chen H, Dong Y, Saunders D, Orock A, Hodges E, Colijn S, Mamedova N, Towner RA. de Souza PC, et al. Among authors: lupu f. Am J Nucl Med Mol Imaging. 2015 Jun 15;5(4):363-78. eCollection 2015. Am J Nucl Med Mol Imaging. 2015. PMID: 26269774 Free PMC article.
195 results