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Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study.
Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R, Comoretto RI, Mizia-Malarz A, Moscatelli A, Sánchez-Martín M, Willems J, Rogerson CM, Bennett TD, Luo Y, Atreya MR, Faustino EVS, Geva A, Weiss SL, Schlapbach LJ, Sanchez-Pinto LN; POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric & Neonatal Intensive Care), and; Novel Data-Driven Sepsis Phenotypes in Children study group. Wösten-van Asperen RM, et al. Among authors: luo y. EClinicalMedicine. 2023 Oct 5;65:102252. doi: 10.1016/j.eclinm.2023.102252. eCollection 2023 Nov. EClinicalMedicine. 2023. PMID: 37842550 Free PMC article.
Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock.
Sanchez-Pinto LN, Bennett TD, Stroup EK, Luo Y, Atreya M, Bubeck Wardenburg J, Chong G, Geva A, Faustino EVS, Farris RW, Hall MW, Rogerson C, Shah SS, Weiss SL, Khemani RG. Sanchez-Pinto LN, et al. Among authors: luo y. Pediatr Crit Care Med. 2023 Oct 1;24(10):795-806. doi: 10.1097/PCC.0000000000003292. Epub 2023 Jun 5. Pediatr Crit Care Med. 2023. PMID: 37272946 Free PMC article.
Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock.
Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ, Baines T, Haileselassie B, Thomas NJ, Luo Y, Sanchez-Pinto LN; Novel Data-Driven Sepsis Phenotypes in Children Study and the Genomics of Pediatric Septic Shock Investigators. Atreya MR, et al. Among authors: luo y. Pediatr Crit Care Med. 2024 Mar 11. doi: 10.1097/PCC.0000000000003499. Online ahead of print. Pediatr Crit Care Med. 2024. PMID: 38465952
Informative missingness: What can we learn from patterns in missing laboratory data in the electronic health record?
Tan ALM, Getzen EJ, Hutch MR, Strasser ZH, Gutiérrez-Sacristán A, Le TT, Dagliati A, Morris M, Hanauer DA, Moal B, Bonzel CL, Yuan W, Chiudinelli L, Das P, Zhang HG, Aronow BJ, Avillach P, Brat GA, Cai T, Hong C, La Cava WG, Hooi Will Loh H, Luo Y, Murphy SN, Yuan Hgiam K, Omenn GS, Patel LP, Jebathilagam Samayamuthu M, Shriver ER, Shakeri Hossein Abad Z, Tan BWL, Visweswaran S, Wang X, Weber GM, Xia Z, Verdy B; COVID-19 by EHR (4CE); Long Q, Mowery DL, Holmes JH. Tan ALM, et al. Among authors: luo y. J Biomed Inform. 2023 Mar;139:104306. doi: 10.1016/j.jbi.2023.104306. Epub 2023 Feb 3. J Biomed Inform. 2023. PMID: 36738870 Free PMC article.
Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.
Gupta Y, Friedman DJ, McNulty MT, Khan A, Lane B, Wang C, Ke J, Jin G, Wooden B, Knob AL, Lim TY, Appel GB, Huggins K, Liu L, Mitrotti A, Stangl MC, Bomback A, Westland R, Bodria M, Marasa M, Shang N, Cohen DJ, Crew RJ, Morello W, Canetta P, Radhakrishnan J, Martino J, Liu Q, Chung WK, Espinoza A, Luo Y, Wei WQ, Feng Q, Weng C, Fang Y, Kullo IJ, Naderian M, Limdi N, Irvin MR, Tiwari H, Mohan S, Rao M, Dube GK, Chaudhary NS, Gutiérrez OM, Judd SE, Cushman M, Lange LA, Lange EM, Bivona DL, Verbitsky M, Winkler CA, Kopp JB, Santoriello D, Batal I, Pinheiro SVB, Oliveira EA, Simoes E Silva AC, Pisani I, Fiaccadori E, Lin F, Gesualdo L, Amoroso A, Ghiggeri GM, D'Agati VD, Magistroni R, Kenny EE, Loos RJF, Montini G, Hildebrandt F, Paul DS, Petrovski S, Goldstein DB, Kretzler M, Gbadegesin R, Gharavi AG, Kiryluk K, Sampson MG, Pollak MR, Sanna-Cherchi S. Gupta Y, et al. Among authors: luo y. Nat Commun. 2023 Nov 30;14(1):7836. doi: 10.1038/s41467-023-43020-9. Nat Commun. 2023. PMID: 38036523 Free PMC article.
Using electronic health records to enhance surveillance of diabetes in children, adolescents and young adults: a study protocol for the DiCAYA Network.
Hirsch AG, Conderino S, Crume TL, Liese AD, Bellatorre A, Bendik S, Divers J, Anthopolos R, Dixon BE, Guo Y, Imperatore G, Lee DC, Reynolds K, Rosenman M, Shao H, Utidjian L, Thorpe LE; DiCAYA Study Group. Hirsch AG, et al. BMJ Open. 2024 Jan 17;14(1):e073791. doi: 10.1136/bmjopen-2023-073791. BMJ Open. 2024. PMID: 38233060 Free PMC article.
A retrospective cohort analysis leveraging augmented intelligence to characterize long COVID in the electronic health record: A precision medicine framework.
Strasser ZH, Dagliati A, Shakeri Hossein Abad Z, Klann JG, Wagholikar KB, Mesa R, Visweswaran S, Morris M, Luo Y, Henderson DW, Samayamuthu MJ; Consortium for Clinical Characterization of COVID-19 by EHR (4CE); Omenn GS, Xia Z, Holmes JH, Estiri H, Murphy SN. Strasser ZH, et al. Among authors: luo y. PLOS Digit Health. 2023 Jul 25;2(7):e0000301. doi: 10.1371/journal.pdig.0000301. eCollection 2023 Jul. PLOS Digit Health. 2023. PMID: 37490472 Free PMC article.
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