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Sequential treatment with AT-101 enhances cisplatin chemosensitivity in human non-small cell lung cancer cells through inhibition of apurinic/apyrimidinic endonuclease 1-activated IL-6/STAT3 signaling pathway.
Ren T, Shan J, Qing Y, Qian C, Li Q, Lu G, Li M, Li C, Peng Y, Luo H, Zhang S, Zhang W, Wang D, Zhou SF. Ren T, et al. Among authors: luo h. Drug Des Devel Ther. 2014 Dec 12;8:2517-29. doi: 10.2147/DDDT.S71432. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25548514 Free PMC article.
A randomized, double-blind, placebo-controlled study of B-cell lymphoma 2 homology 3 mimetic gossypol combined with docetaxel and cisplatin for advanced non-small cell lung cancer with high expression of apurinic/apyrimidinic endonuclease 1.
Wang Y, Li X, Zhang L, Li M, Dai N, Luo H, Shan J, Yang X, Xu M, Feng Y, Xu C, Qian C, Wang D. Wang Y, et al. Among authors: luo h. Invest New Drugs. 2020 Dec;38(6):1862-1871. doi: 10.1007/s10637-020-00927-0. Epub 2020 Jun 11. Invest New Drugs. 2020. PMID: 32529467 Free PMC article. Clinical Trial.
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