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A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein.
Tang A, Chen Z, Cox KS, Su HP, Callahan C, Fridman A, Zhang L, Patel SB, Cejas PJ, Swoyer R, Touch S, Citron MP, Govindarajan D, Luo B, Eddins M, Reid JC, Soisson SM, Galli J, Wang D, Wen Z, Heidecker GJ, Casimiro DR, DiStefano DJ, Vora KA. Tang A, et al. Among authors: luo b. Nat Commun. 2019 Sep 12;10(1):4153. doi: 10.1038/s41467-019-12137-1. Nat Commun. 2019. PMID: 31515478 Free PMC article.
Characterization of humoral and cell-mediated immunity induced by mRNA vaccines expressing influenza hemagglutinin stem and nucleoprotein in mice and nonhuman primates.
Flynn JA, Weber T, Cejas PJ, Cox KS, Touch S, Austin LA, Ou Y, Citron MP, Luo B, Gindy ME, Bahl K, Ciaramella G, Espeseth AS, Zhang L. Flynn JA, et al. Among authors: luo b. Vaccine. 2022 Jul 30;40(32):4412-4423. doi: 10.1016/j.vaccine.2022.03.063. Epub 2022 Jun 6. Vaccine. 2022. PMID: 35680500
Preclinical immunogenicity and efficacy of a candidate COVID-19 vaccine based on a vesicular stomatitis virus-SARS-CoV-2 chimera.
Espeseth AS, Yuan M, Citron M, Reiserova L, Morrow G, Wilson A, Horton M, Rukhman M, Kinek K, Hou F, Li SL, Li F, Choi Y, Heidecker G, Luo B, Wu G, Zhang L, Strable E, DeStefano J, Secore S, Mukhopadhyay TK, Richardson DD, Sayeed E, Welch LS, Bett AJ, Feinberg MB, Gupta SB, Cooper CL, Parks CL. Espeseth AS, et al. Among authors: luo b. EBioMedicine. 2022 Aug;82:104203. doi: 10.1016/j.ebiom.2022.104203. Epub 2022 Jul 30. EBioMedicine. 2022. PMID: 35915046 Free PMC article.
Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface.
Xiao X, Wen Z, Chen Q, Shipman JM, Kostas J, Reid JC, Warren C, Tang A, Luo B, O'Donnell G, Fridman A, Chen Z, Vora KA, Zhang L, Su H-P, Eddins MJ. Xiao X, et al. Among authors: luo b. J Virol. 2023 Dec 21;97(12):e0105223. doi: 10.1128/jvi.01052-23. Epub 2023 Nov 30. J Virol. 2023. PMID: 38032197 Free PMC article.
Proof-of-concept Studies for siRNA-mediated Gene Silencing for Coagulation Factors in Rat and Rabbit.
Chen Z, Luo B, Cai TQ, Thankappan A, Xu Y, Wu W, DiMuzio J, Lifsted T, DiPietro M, Disa J, Ng B, Leander K, Clark S, Hoos L, Zhou Y, Jochnowitz N, Jachec C, Szczerba P, Gindy ME, Strapps W, Sepp-Lorenzino L, Seiffert DA, Lubbers L, Tadin-Strapps M. Chen Z, et al. Among authors: luo b. Mol Ther Nucleic Acids. 2015 Jan 27;4(1):e224. doi: 10.1038/mtna.2014.75. Mol Ther Nucleic Acids. 2015. PMID: 25625614 Free PMC article.
Applicability of in vitro-in vivo translation of cathepsin K inhibition from animal species to human with the use of free-drug hypothesis.
Ma B, Luo B, Euler DH, Cusick TE, Wesolowski G, Glantschnig H, Duong LT, Ou Y, Carroll SS, Lubbers LS. Ma B, et al. Among authors: luo b. Naunyn Schmiedebergs Arch Pharmacol. 2017 Apr;390(4):435-441. doi: 10.1007/s00210-017-1356-5. Epub 2017 Feb 20. Naunyn Schmiedebergs Arch Pharmacol. 2017. PMID: 28220210 Clinical Trial.
3,316 results