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Screening for antibacterial inhibitors of the UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) using a high-throughput mass spectrometry assay.
Langsdorf EF, Malikzay A, Lamarr WA, Daubaras D, Kravec C, Zhang R, Hart R, Monsma F, Black T, Ozbal CC, Miesel L, Lunn CA. Langsdorf EF, et al. Among authors: lunn ca. J Biomol Screen. 2010 Jan;15(1):52-61. doi: 10.1177/1087057109355319. Epub 2009 Dec 17. J Biomol Screen. 2010. PMID: 20019290
Expansion of SAR studies on triaryl bis sulfone cannabinoid CB2 receptor ligands.
Tong L, Shankar BB, Chen L, Rizvi R, Kelly J, Gilbert E, Huang C, Yang DY, Kozlowski JA, Shih NY, Gonsiorek W, Hipkin RW, Malikzay A, Lunn CA, Lundell DJ. Tong L, et al. Among authors: lunn ca. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6785-9. doi: 10.1016/j.bmcl.2010.08.126. Epub 2010 Aug 31. Bioorg Med Chem Lett. 2010. PMID: 20850969
Non-aromatic A-ring replacement in the triaryl bis-sulfone CB2 receptor inhibitors.
Gilbert EJ, Zhou G, Wong MK, Tong L, Shankar BB, Huang C, Kelly J, Lavey BJ, McCombie SW, Chen L, Rizvi R, Dong Y, Shu Y, Kozlowski JA, Shih NY, Hipkin RW, Gonsiorek W, Malikzay A, Lunn CA, Favreau L, Lundell DJ. Gilbert EJ, et al. Among authors: lunn ca. Bioorg Med Chem Lett. 2010 Jan 15;20(2):608-11. doi: 10.1016/j.bmcl.2009.11.084. Epub 2009 Nov 22. Bioorg Med Chem Lett. 2010. PMID: 20005710
Triaryl bis-sulfones as cannabinoid-2 receptor ligands: SAR studies.
Shankar BB, Lavey BJ, Zhou G, Spitler JA, Tong L, Rizvi R, Yang DY, Wolin R, Kozlowski JA, Shih NY, Wu J, Hipkin RW, Gonsiorek W, Lunn CA. Shankar BB, et al. Among authors: lunn ca. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4417-20. doi: 10.1016/j.bmcl.2005.07.023. Bioorg Med Chem Lett. 2005. PMID: 16115769
50 results