Lund ME - Search Results

1

The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages.

Alvarado R, To J, Lund ME, Pinar A, Mansell A, Robinson MW, O'Brien BA, Dalton JP, Donnelly S. Alvarado R, et al. Among authors: lund me. FASEB J. 2017 Jan;31(1):85-95. doi: 10.1096/fj.201500093R. Epub 2016 Sep 28. FASEB J. 2017. PMID: 27682204

2

A helminth cathelicidin-like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPase.

Robinson MW, Alvarado R, To J, Hutchinson AT, Dowdell SN, Lund M, Turnbull L, Whitchurch CB, O'Brien BA, Dalton JP, Donnelly S. Robinson MW, et al. FASEB J. 2012 Nov;26(11):4614-27. doi: 10.1096/fj.12-213876. Epub 2012 Aug 7. FASEB J. 2012. PMID: 22872675

3

Fasciola hepatica hijacks host macrophage miRNA machinery to modulate early innate immune responses.

Tran N, Ricafrente A, To J, Lund M, Marques TM, Gama-Carvalho M, Cwiklinski K, Dalton JP, Donnelly S. Tran N, et al. Sci Rep. 2021 Mar 24;11(1):6712. doi: 10.1038/s41598-021-86125-1. Sci Rep. 2021. PMID: 33762636 Free PMC article.

4

The parasite-derived peptide FhHDM-1 activates the PI3K/Akt pathway to prevent cytokine-induced apoptosis of β-cells.

Camaya I, Mok TY, Lund M, To J, Braidy N, Robinson MW, Santos J, O'Brien B, Donnelly S. Camaya I, et al. J Mol Med (Berl). 2021 Nov;99(11):1605-1621. doi: 10.1007/s00109-021-02122-x. Epub 2021 Aug 10. J Mol Med (Berl). 2021. PMID: 34374810

5

Secreted proteins from the helminth Fasciola hepatica inhibit the initiation of autoreactive T cell responses and prevent diabetes in the NOD mouse.

Lund ME, O'Brien BA, Hutchinson AT, Robinson MW, Simpson AM, Dalton JP, Donnelly S. Lund ME, et al. PLoS One. 2014 Jan 21;9(1):e86289. doi: 10.1371/journal.pone.0086289. eCollection 2014. PLoS One. 2014. PMID: 24466007 Free PMC article.

6

A parasite-derived 68-mer peptide ameliorates autoimmune disease in murine models of Type 1 diabetes and multiple sclerosis.

Lund ME, Greer J, Dixit A, Alvarado R, McCauley-Winter P, To J, Tanaka A, Hutchinson AT, Robinson MW, Simpson AM, O'Brien BA, Dalton JP, Donnelly S. Lund ME, et al. Sci Rep. 2016 Nov 24;6:37789. doi: 10.1038/srep37789. Sci Rep. 2016. PMID: 27883079 Free PMC article.

7

Selection of reliable reference genes for the normalisation of gene expression levels following time course LPS stimulation of murine bone marrow derived macrophages.

Tanaka A, To J, O'Brien B, Donnelly S, Lund M. Tanaka A, et al. BMC Immunol. 2017 Oct 3;18(1):43. doi: 10.1186/s12865-017-0223-y. BMC Immunol. 2017. PMID: 28974200 Free PMC article.

8

The parasitic 68-mer peptide FhHDM-1 inhibits mixed granulocytic inflammation and airway hyperreactivity in experimental asthma.

Tanaka A, Allam VSRR, Simpson J, Tiberti N, Shiels J, To J, Lund M, Combes V, Weldon S, Taggart C, Dalton JP, Phipps S, Sukkar MB, Donnelly S. Tanaka A, et al. J Allergy Clin Immunol. 2018 Jun;141(6):2316-2319. doi: 10.1016/j.jaci.2018.01.050. Epub 2018 Mar 6. J Allergy Clin Immunol. 2018. PMID: 29522851 No abstract available.

9

The choice of phorbol 12-myristate 13-acetate differentiation protocol influences the response of THP-1 macrophages to a pro-inflammatory stimulus.

Lund ME, To J, O'Brien BA, Donnelly S. Lund ME, et al. J Immunol Methods. 2016 Mar;430:64-70. doi: 10.1016/j.jim.2016.01.012. Epub 2016 Jan 27. J Immunol Methods. 2016. PMID: 26826276

10

Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation.

Thivierge K, Cotton S, Schaefer DA, Riggs MW, To J, Lund ME, Robinson MW, Dalton JP, Donnelly SM. Thivierge K, et al. Among authors: lund me. PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2307. doi: 10.1371/journal.pntd.0002307. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23875042 Free PMC article.

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