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Vasodilation Elicited by Isoxsuprine, Identified by High-Throughput Virtual Screening of Compound Libraries, Involves Activation of the NO/cGMP and H₂S/KATP Pathways and Blockade of α₁-Adrenoceptors and Calcium Channels.
Medina-Ruiz D, Erreguin-Luna B, Luna-Vázquez FJ, Romo-Mancillas A, Rojas-Molina A, Ibarra-Alvarado C. Medina-Ruiz D, et al. Among authors: luna vazquez fj. Molecules. 2019 Mar 11;24(5):987. doi: 10.3390/molecules24050987. Molecules. 2019. PMID: 30862086 Free PMC article.
Vasodilator activity of Poecilotheria ornata venom involves activation of the NO/cGMP pathway and inhibition of calcium influx to vascular smooth muscle cells.
de Jesus-López E, Cuéllar-Balleza L, Díaz-Peña LF, Luna-Vázquez FJ, Ibarra-Alvarado C, García-Arredondo JA. de Jesus-López E, et al. Among authors: luna vazquez fj. Toxicon X. 2023 May 20;19:100159. doi: 10.1016/j.toxcx.2023.100159. eCollection 2023 Sep. Toxicon X. 2023. PMID: 37251689 Free PMC article.
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