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Page 1
Solubilizer Tag Effect on PD-L1/Inhibitor Binding Properties for m-Terphenyl Derivatives.
Surmiak E, Ząber J, Plewka J, Wojtanowicz G, Kocik-Krol J, Kruc O, Muszak D, Rodríguez I, Musielak B, Viviano M, Castellano S, Skalniak L, Magiera-Mularz K, Holak TA, Kalinowska-Tłuścik J. Surmiak E, et al. Among authors: skalniak l. ACS Med Chem Lett. 2023 Dec 14;15(1):36-44. doi: 10.1021/acsmedchemlett.3c00306. eCollection 2024 Jan 11. ACS Med Chem Lett. 2023. PMID: 38229762 Free PMC article.
A combined approach of structure-based virtual screening and NMR to interrupt the PD-1/PD-L1 axis: Biphenyl-benzimidazole containing compounds as novel PD-L1 inhibitors.
Donati G, Viviano M, D'Amore VM, Cipriano A, Diakogiannaki I, Amato J, Tomassi S, Brancaccio D, Russomanno P, Di Leva FS, Arosio D, Seneci P, Taliani S, Magiera-Mularz K, Musielak B, Skalniak L, Holak TA, Castellano S, La Pietra V, Marinelli L. Donati G, et al. Among authors: skalniak l. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300583. doi: 10.1002/ardp.202300583. Epub 2023 Dec 18. Arch Pharm (Weinheim). 2024. PMID: 38110703
Structural and biological characterization of pAC65, a macrocyclic peptide that blocks PD-L1 with equivalent potency to the FDA-approved antibodies.
Rodriguez I, Kocik-Krol J, Skalniak L, Musielak B, Wisniewska A, Ciesiołkiewicz A, Berlicki Ł, Plewka J, Grudnik P, Stec M, Siedlar M, Holak TA, Magiera-Mularz K. Rodriguez I, et al. Among authors: skalniak l. Mol Cancer. 2023 Sep 7;22(1):150. doi: 10.1186/s12943-023-01853-4. Mol Cancer. 2023. PMID: 37679783 Free PMC article.
Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors.
Ważyńska MA, Butera R, Requesens M, Plat A, Zarganes-Tzitzikas T, Neochoritis CG, Plewka J, Skalniak L, Kocik-Krol J, Musielak B, Magiera-Mularz K, Rodriguez I, Blok SN, de Bruyn M, Nijman HW, Elsinga PH, Holak TA, Dömling A. Ważyńska MA, et al. Among authors: skalniak l. J Med Chem. 2023 Jul 27;66(14):9577-9591. doi: 10.1021/acs.jmedchem.3c00254. Epub 2023 Jul 14. J Med Chem. 2023. PMID: 37450644 Free PMC article.
A study of the interactions between human osteoblast-like cells and polymer composites with functionalized graphene derivatives using 2D correlation spectroscopy (2D-COS).
Kołodziej A, Wesełucha-Birczyńska A, Długoń E, Świętek M, Gubernat M, Skalniak Ł, Błażewicz M. Kołodziej A, et al. Among authors: skalniak l. Spectrochim Acta A Mol Biomol Spectrosc. 2023 Jan 15;285:121862. doi: 10.1016/j.saa.2022.121862. Epub 2022 Sep 10. Spectrochim Acta A Mol Biomol Spectrosc. 2023. PMID: 36122465
Biphenyl Ether Analogs Containing Pomalidomide as Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.
Shaabani S, Gadina L, Surmiak E, Wang Z, Zhang B, Butera R, Zarganes-Tzitzikas T, Rodriguez I, Kocik-Krol J, Magiera-Mularz K, Skalniak L, Dömling A, Holak TA. Shaabani S, et al. Among authors: skalniak l. Molecules. 2022 May 27;27(11):3454. doi: 10.3390/molecules27113454. Molecules. 2022. PMID: 35684392 Free PMC article.
PD-L1 Inhibitors: Different Classes, Activities, and Mechanisms of Action.
Surmiak E, Magiera-Mularz K, Musielak B, Muszak D, Kocik-Krol J, Kitel R, Plewka J, Holak TA, Skalniak L. Surmiak E, et al. Among authors: skalniak l. Int J Mol Sci. 2021 Oct 30;22(21):11797. doi: 10.3390/ijms222111797. Int J Mol Sci. 2021. PMID: 34769226 Free PMC article.
Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction.
Muszak D, Surmiak E, Plewka J, Magiera-Mularz K, Kocik-Krol J, Musielak B, Sala D, Kitel R, Stec M, Weglarczyk K, Siedlar M, Dömling A, Skalniak L, Holak TA. Muszak D, et al. Among authors: skalniak l. J Med Chem. 2021 Aug 12;64(15):11614-11636. doi: 10.1021/acs.jmedchem.1c00957. Epub 2021 Jul 27. J Med Chem. 2021. PMID: 34313116 Free PMC article.
41 results