Fas receptor induces apoptosis of synovial bone and cartilage progenitor populations and promotes bone loss in antigen-induced arthritis.
Lazić Mosler E, Lukač N, Flegar D, Fadljević M, Radanović I, Cvija H, Kelava T, Ivčević S, Šućur A, Markotić A, Katavić V, Marušić A, Grčević D, Kovačić N.
Lazić Mosler E, et al. Among authors: lukac n.
FASEB J. 2019 Mar;33(3):3330-3342. doi: 10.1096/fj.201801426R. Epub 2018 Nov 1.
FASEB J. 2019.
PMID: 30383451
These results suggest that Fas-induced apoptosis of early CD200(+) osteoprogenitor population represents potential mechanism underlying the impaired bone formation in arthritis, so their preservation may represent the bone-protective mechanism during arthritis.-Lazic Mosler, E., …
These results suggest that Fas-induced apoptosis of early CD200(+) osteoprogenitor population represents potential mechanism underlying the …