Luk K - Search Results

1

Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search.

Janssen B, Tian G, Lengyel-Zhand Z, Hsieh CJ, Lougee MG, Riad A, Xu K, Hou C, Weng CC, Lopresti BJ, Kim HJ, Pagar VV, Ferrie JJ, Garcia BA, Mathis CA, Luk K, Petersson EJ, Mach RH. Janssen B, et al. Among authors: luk k. Mol Imaging Biol. 2023 Aug;25(4):704-719. doi: 10.1007/s11307-023-01814-9. Epub 2023 Mar 29. Mol Imaging Biol. 2023. PMID: 36991273

2

Stereotaxic Targeting of Alpha-Synuclein Pathology in Mouse Brain Using Preformed Fibrils.

Zhang B, Kehm V, Gathagan R, Leight SN, Trojanowski JQ, Lee VM, Luk KC. Zhang B, et al. Methods Mol Biol. 2019;1948:45-57. doi: 10.1007/978-1-4939-9124-2_5. Methods Mol Biol. 2019. PMID: 30771169 Free PMC article.

3

Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD Samples.

Puentes LN, Lengyel-Zhand Z, Lee JY, Hsieh CJ, Schneider ME Jr, Edwards KJ, Luk KC, Lee VM, Trojanowski JQ, Mach RH. Puentes LN, et al. Front Aging Neurosci. 2021 Jun 18;13:704041. doi: 10.3389/fnagi.2021.704041. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34220490 Free PMC article.

4

α-Synuclein arginylation in the human brain.

Zhao J, Pan B, Fina M, Huang Y, Shimogawa M, Luk KC, Rhoades E, Petersson EJ, Dong DW, Kashina A. Zhao J, et al. Transl Neurodegener. 2022 Apr 8;11(1):20. doi: 10.1186/s40035-022-00295-0. Transl Neurodegener. 2022. PMID: 35395956 Free PMC article.

5

A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy.

Kim HY, Chia WK, Hsieh CJ, Saturnino Guarino D, Graham TJA, Lengyel-Zhand Z, Schneider M, Tomita C, Lougee MG, Kim HJ, Pagar VV, Lee H, Hou C, Garcia BA, Petersson EJ, O'Shea J, Kotzbauer PT, Mathis CA, Lee VM, Luk KC, Mach RH. Kim HY, et al. J Med Chem. 2023 Sep 14;66(17):12185-12202. doi: 10.1021/acs.jmedchem.3c00779. Epub 2023 Aug 31. J Med Chem. 2023. PMID: 37651366

6

Positron Emission Tomography with [¹⁸F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy.

Gallagher E, Hou C, Zhu Y, Hsieh CJ, Lee H, Li S, Xu K, Henderson P, Chroneos R, Sheldon M, Riley S, Luk KC, Mach RH, McManus MJ. Gallagher E, et al. Among authors: luk kc. Int J Mol Sci. 2024 May 1;25(9):4943. doi: 10.3390/ijms25094943. Int J Mol Sci. 2024. PMID: 38732162 Free PMC article.

7

Cell-to-Cell Transmission of Tau and α-Synuclein.

Uemura N, Uemura MT, Luk KC, Lee VM, Trojanowski JQ. Uemura N, et al. Trends Mol Med. 2020 Oct;26(10):936-952. doi: 10.1016/j.molmed.2020.03.012. Epub 2020 May 1. Trends Mol Med. 2020. PMID: 32371172 Free PMC article. Review.

8

O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology.

Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR. Balana AT, et al. Nat Chem Biol. 2024 May;20(5):646-655. doi: 10.1038/s41589-024-01551-2. Epub 2024 Feb 12. Nat Chem Biol. 2024. PMID: 38347213 Free PMC article.

9

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice.

Luk KC, Kehm VM, Zhang B, O'Brien P, Trojanowski JQ, Lee VM. Luk KC, et al. J Exp Med. 2012 May 7;209(5):975-86. doi: 10.1084/jem.20112457. Epub 2012 Apr 16. J Exp Med. 2012. PMID: 22508839 Free PMC article.

10

Α-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration.

Tran HT, Chung CH, Iba M, Zhang B, Trojanowski JQ, Luk KC, Lee VM. Tran HT, et al. Cell Rep. 2014 Jun 26;7(6):2054-65. doi: 10.1016/j.celrep.2014.05.033. Epub 2014 Jun 12. Cell Rep. 2014. PMID: 24931606 Free PMC article.

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