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THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates.
Reithuber E, Wixe T, Ludwig KC, Müller A, Uvell H, Grein F, Lindgren AEG, Muschiol S, Nannapaneni P, Eriksson A, Schneider T, Normark S, Henriques-Normark B, Almqvist F, Mellroth P. Reithuber E, et al. Among authors: ludwig kc. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2108244118. doi: 10.1073/pnas.2108244118. Proc Natl Acad Sci U S A. 2021. PMID: 34785593 Free PMC article.
Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic Hypeptin.
Wirtz DA, Ludwig KC, Arts M, Marx CE, Krannich S, Barac P, Kehraus S, Josten M, Henrichfreise B, Müller A, König GM, Peoples AJ, Nitti A, Spoering AL, Ling LL, Lewis K, Crüsemann M, Schneider T. Wirtz DA, et al. Among authors: ludwig kc. Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13579-13586. doi: 10.1002/anie.202102224. Epub 2021 May 7. Angew Chem Int Ed Engl. 2021. PMID: 33768646 Free PMC article.
Host Defense Peptides: Dual Antimicrobial and Immunomodulatory Action.
Drayton M, Deisinger JP, Ludwig KC, Raheem N, Müller A, Schneider T, Straus SK. Drayton M, et al. Among authors: ludwig kc. Int J Mol Sci. 2021 Oct 16;22(20):11172. doi: 10.3390/ijms222011172. Int J Mol Sci. 2021. PMID: 34681833 Free PMC article. Review.
An antibiotic from an uncultured bacterium binds to an immutable target.
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, De Benedetti S, Krueger AM, Vermeulen BJA, Harbig T, Lavore F, Kumar R, Honorato RV, Grein F, Nieselt K, Liu Y, Bonvin AMJJ, Baldus M, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwalen CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, Weingarth M. Shukla R, et al. Among authors: ludwig kc. Cell. 2023 Sep 14;186(19):4059-4073.e27. doi: 10.1016/j.cell.2023.07.038. Epub 2023 Aug 22. Cell. 2023. PMID: 37611581 Free article.
Investigations on the Degradation of the Bile Salt Cholate via the 9,10-Seco-Pathway Reveals the Formation of a Novel Recalcitrant Steroid Compound by a Side Reaction in Sphingobium sp. Strain Chol11.
Feller FM, Eilebrecht S, Nedielkov R, Yücel O, Alvincz J, Salinas G, Ludwig KC, Möller H, Philipp B. Feller FM, et al. Among authors: ludwig kc. Microorganisms. 2021 Oct 14;9(10):2146. doi: 10.3390/microorganisms9102146. Microorganisms. 2021. PMID: 34683472 Free PMC article.
12 results