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HIV vaccines induce CD8+ T cells with low antigen receptor sensitivity.
Migueles SA, Nettere DM, Gavil NV, Wang LT, Toulmin SA, Kelly EP, Ward AJ, Lin S, Thompson SA, Peterson BA, Abdeen CS, Sclafani CR, Pryal PF, Leach BG, Ludwig AK, Rogan DC, Przygonska PA, Cattani A, Imamichi H, Sachs A, Cafri G, Huang NN, Patamawenu A, Liang CJ, Hallahan CW, Kambach DM, Han EX, Coupet T, Chen J, Moir SL, Chun TW, Coates EE, Ledgerwood J, Schmidt J, Taillandier-Coindard M, Michaux J, Pak H, Bassani-Sternberg M, Frahm N, McElrath MJ, Connors M. Migueles SA, et al. Among authors: ludwig ak. Science. 2023 Dec 15;382(6676):1270-1276. doi: 10.1126/science.adg0514. Epub 2023 Dec 14. Science. 2023. PMID: 38096385
Antigenic Restimulation of Virus-Specific Memory CD8+ T Cells Requires Days of Lytic Protein Accumulation for Maximal Cytotoxic Capacity.
Migueles SA, Rogan DC, Gavil NV, Kelly EP, Toulmin SA, Wang LT, Lack J, Ward AJ, Pryal PF, Ludwig AK, Medina RG, Apple BJ, Toumanios CN, Poole AL, Rehm CA, Jones SE, Liang CJ, Connors M. Migueles SA, et al. Among authors: ludwig ak. J Virol. 2020 Nov 9;94(23):e01595-20. doi: 10.1128/JVI.01595-20. Print 2020 Nov 9. J Virol. 2020. PMID: 32907983 Free PMC article.
Targeting osteoarthritis-associated galectins and an induced effector class by a ditopic bifunctional reagent: Impact of its glycan part on binding measured in the tissue context.
Manning JC, Baldoneschi V, Romero-Hernández LL, Pichler KM, GarcÍa Caballero G, André S, Kutzner TJ, Ludwig AK, Zullo V, Richichi B, Windhager R, Kaltner H, Toegel S, Gabius HJ, Murphy PV, Nativi C. Manning JC, et al. Among authors: ludwig ak. Bioorg Med Chem. 2022 Dec 1;75:117068. doi: 10.1016/j.bmc.2022.117068. Epub 2022 Oct 18. Bioorg Med Chem. 2022. PMID: 36327696
Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1.
Janssen M, Schmidt C, Bruch PM, Blank MF, Rohde C, Waclawiczek A, Heid D, Renders S, Göllner S, Vierbaum L, Besenbeck B, Herbst SA, Knoll M, Kolb C, Przybylla A, Weidenauer K, Ludwig AK, Fabre M, Gu M, Schlenk RF, Stölzel F, Bornhäuser M, Röllig C, Platzbecker U, Baldus C, Serve H, Sauer T, Raffel S, Pabst C, Vassiliou G, Vick B, Jeremias I, Trumpp A, Krijgsveld J, Müller-Tidow C, Dietrich S. Janssen M, et al. Among authors: ludwig ak. Blood. 2022 Dec 15;140(24):2594-2610. doi: 10.1182/blood.2021014241. Blood. 2022. PMID: 35857899 Free article.
Exploring the Galectin Network by Light and Fluorescence Microscopy.
García Caballero G, Manning JC, Gabba A, Beckwith D, FitzGerald FG, Kutzner TJ, Ludwig AK, Kaltner H, Murphy PV, Cudic M, Gabius HJ. García Caballero G, et al. Among authors: ludwig ak. Methods Mol Biol. 2022;2442:307-338. doi: 10.1007/978-1-0716-2055-7_17. Methods Mol Biol. 2022. PMID: 35320533
79 results