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Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice.
van der Vorst EPC, Maas SL, Theodorou K, Peters LJF, Jin H, Rademakers T, Gijbels MJ, Rousch M, Jansen Y, Weber C, Lehrke M, Lebherz C, Yildiz D, Ludwig A, Bentzon JF, Biessen EAL, Donners MMPC. van der Vorst EPC, et al. Among authors: ludwig a. Front Cardiovasc Med. 2023 Jan 27;10:974918. doi: 10.3389/fcvm.2023.974918. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 36776254 Free PMC article.
Gene-expression profiling of laser-dissected islets and studies in deficient mice reveal chemokines as differential driving force of type 1 diabetes.
Bender C, Müller P, Tondello C, Horn J, Holdener M, Lasch S, Bayer M, Pfeilschifter JM, Tacke F, Ludwig A, Hansmann ML, Döring C, Hintermann E, Christen U. Bender C, et al. Among authors: ludwig a. J Autoimmun. 2024 Feb;143:103161. doi: 10.1016/j.jaut.2023.103161. Epub 2023 Dec 22. J Autoimmun. 2024. PMID: 38141419
Protean proteases: at the cutting edge of lung diseases.
Taggart C, Mall MA, Lalmanach G, Cataldo D, Ludwig A, Janciauskiene S, Heath N, Meiners S, Overall CM, Schultz C, Turk B, Borensztajn KS. Taggart C, et al. Among authors: ludwig a. Eur Respir J. 2017 Feb 8;49(2):1501200. doi: 10.1183/13993003.01200-2015. Print 2017 Feb. Eur Respir J. 2017. PMID: 28179435 Free article. Review.
Repeated Injection of Very Small Superparamagnetic Iron Oxide Particles (VSOPs) in Murine Atherosclerosis: A Safety Study.
Haase T, Ludwig A, Stach A, Mohtashamdolatshahi A, Hauptmann R, Mundhenk L, Kratz H, Metzkow S, Kader A, Freise C, Mueller S, Stolzenburg N, Radon P, Liebl M, Wiekhorst F, Hamm B, Taupitz M, Schnorr J. Haase T, et al. Among authors: ludwig a. Nanomaterials (Basel). 2024 Apr 28;14(9):773. doi: 10.3390/nano14090773. Nanomaterials (Basel). 2024. PMID: 38727367 Free PMC article.
Neutral sphingomyelinase controls acute and chronic alcohol effects on brain activity.
Wank I, Mittmann C, Kreitz S, Chestnykh D, Mühle C, Kornhuber J, Ludwig A, Kalinichenko LS, Müller CP, Hess A. Wank I, et al. Among authors: ludwig a. Neuropharmacology. 2024 Apr 16;253:109948. doi: 10.1016/j.neuropharm.2024.109948. Online ahead of print. Neuropharmacology. 2024. PMID: 38636728 Free article.
Lack of Laminar Shear Stress Facilitates the Endothelial Uptake of Very Small Superparamagnetic Iron Oxide Nanoparticles by Modulating the Endothelial Surface Layer.
Twamley SG, Gimber N, Sánchez-Ibarra HE, Christaller T, Isakzai V, Kratz H, Mitra R, Kampen L, Stach A, Heilmann H, Söhl-Kielczynski B, Ebong EE, Schmoranzer J, Münster-Wandowski A, Ludwig A. Twamley SG, et al. Among authors: ludwig a. Int J Nanomedicine. 2024 Apr 2;19:3123-3142. doi: 10.2147/IJN.S437714. eCollection 2024. Int J Nanomedicine. 2024. PMID: 38585474 Free PMC article.
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity.
Bläsius K, Ludwig L, Knapp S, Flaßhove C, Sonnabend F, Keller D, Tacken N, Gao X, Kahveci-Türköz S, Grannemann C, Babendreyer A, Adrain C, Huth S, Baron JM, Ludwig A, Düsterhöft S. Bläsius K, et al. Among authors: ludwig a. Cell Mol Life Sci. 2024 Feb 27;81(1):102. doi: 10.1007/s00018-024-05132-3. Cell Mol Life Sci. 2024. PMID: 38409522 Free PMC article.
1,285 results