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A recombinant Leishmania amastigote-specific protein, rLiHyG, with adjuvants, protects against infection with Leishmania infantum.
Machado AS, Lage DP, Vale DL, Freitas CS, Linhares FP, Cardoso JMO, Pereira IAG, Ramos FF, Tavares GSV, Ludolf F, Oliveira-da-Silva JA, Bandeira RS, Simões AC, Duarte MC, Oliveira JS, Christodoulides M, Chávez-Fumagalli MA, Roatt BM, Martins VT, Coelho EAF. Machado AS, et al. Among authors: ludolf f. Acta Trop. 2022 Jun;230:106412. doi: 10.1016/j.actatropica.2022.106412. Epub 2022 Mar 16. Acta Trop. 2022. PMID: 35305943
Poloxamer 407 (Pluronic(®) F127)-based polymeric micelles for amphotericin B: In vitro biological activity, toxicity and in vivo therapeutic efficacy against murine tegumentary leishmaniasis.
Mendonça DV, Lage LM, Lage DP, Chávez-Fumagalli MA, Ludolf F, Roatt BM, Menezes-Souza D, Faraco AA, Castilho RO, Tavares CA, Barichello JM, Duarte MC, Coelho EA. Mendonça DV, et al. Among authors: ludolf f. Exp Parasitol. 2016 Oct;169:34-42. doi: 10.1016/j.exppara.2016.07.005. Epub 2016 Jul 15. Exp Parasitol. 2016. PMID: 27427166
A vaccine composed of a hypothetical protein and the eukaryotic initiation factor 5a from Leishmania braziliensis cross-protection against Leishmania amazonensis infection.
Duarte MC, Lage DP, Martins VT, Costa LE, Carvalho AMRS, Ludolf F, Santos TTO, Vale DL, Roatt BM, Menezes-Souza D, Fernandes AP, Tavares CAP, Coelho EAF. Duarte MC, et al. Among authors: ludolf f. Immunobiology. 2017 Feb;222(2):251-260. doi: 10.1016/j.imbio.2016.09.015. Epub 2016 Sep 28. Immunobiology. 2017. PMID: 27693018
Antileishmanial activity of a naphthoquinone derivate against promastigote and amastigote stages of Leishmania infantum and Leishmania amazonensis and its mechanism of action against L. amazonensis species.
Mendonça DVC, Lage DP, Calixto SL, Ottoni FM, Tavares GSV, Ludolf F, Chávez-Fumagalli MA, Schneider MS, Duarte MC, Tavares CAP, Alves RJ, Coimbra ES, Coelho EAF. Mendonça DVC, et al. Among authors: ludolf f. Parasitol Res. 2018 Feb;117(2):391-403. doi: 10.1007/s00436-017-5713-6. Epub 2017 Dec 16. Parasitol Res. 2018. PMID: 29248978
Antileishmanial Activity, Cytotoxicity and Mechanism of Action of Clioquinol Against Leishmania infantum and Leishmania amazonensis Species.
Tavares GSV, Mendonça DVC, Lage DP, Granato JDT, Ottoni FM, Ludolf F, Chávez-Fumagalli MA, Duarte MC, Tavares CAP, Alves RJ, Coimbra ES, Coelho EAF. Tavares GSV, et al. Among authors: ludolf f. Basic Clin Pharmacol Toxicol. 2018 Sep;123(3):236-246. doi: 10.1111/bcpt.12990. Epub 2018 Apr 6. Basic Clin Pharmacol Toxicol. 2018. PMID: 29481714 Free article.
Vaccination with a CD4+ and CD8+ T-cell epitopes-based recombinant chimeric protein derived from Leishmania infantum proteins confers protective immunity against visceral leishmaniasis.
Dias DS, Ribeiro PAF, Martins VT, Lage DP, Costa LE, Chávez-Fumagalli MA, Ramos FF, Santos TTO, Ludolf F, Oliveira JS, Mendes TAO, Silva ES, Galdino AS, Duarte MC, Roatt BM, Menezes-Souza D, Teixeira AL, Coelho EAF. Dias DS, et al. Among authors: ludolf f. Transl Res. 2018 Oct;200:18-34. doi: 10.1016/j.trsl.2018.05.001. Epub 2018 May 22. Transl Res. 2018. PMID: 29908151
A Leishmania hypothetical protein-containing liposome-based formulation is highly immunogenic and induces protection against visceral leishmaniasis.
Ribeiro PAF, Dias DS, Novais MVM, Lage DP, Tavares GSV, Mendonça DVC, Oliveira JS, Chávez-Fumagalli MA, Roatt BM, Duarte MC, Menezes-Souza D, Ludolf F, Tavares CAP, Oliveira MC, Coelho EAF. Ribeiro PAF, et al. Among authors: ludolf f. Cytokine. 2018 Nov;111:131-139. doi: 10.1016/j.cyto.2018.08.019. Epub 2018 Aug 22. Cytokine. 2018. PMID: 30142534
A Pluronic® F127-based polymeric micelle system containing an antileishmanial molecule is immunotherapeutic and effective in the treatment against Leishmania amazonensis infection.
Tavares GSV, Mendonça DVC, Miyazaki CK, Lage DP, Soyer TG, Carvalho LM, Ottoni FM, Dias DS, Ribeiro PAF, Antinarelli LMR, Ludolf F, Duarte MC, Coimbra ES, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Barichello JM, Alves RJ, Coelho EAF. Tavares GSV, et al. Among authors: ludolf f. Parasitol Int. 2019 Feb;68(1):63-72. doi: 10.1016/j.parint.2018.10.005. Epub 2018 Oct 16. Parasitol Int. 2019. PMID: 30339837
63 results